STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rcsBCapsular synthesis regulator component B; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (231 aa)    
Predicted Functional Partners:
yojN
Putative sensor-like histidine kinase yojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 
 0.999
rcsA
Colanic acid capsular biosynthesis activation protein A; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes.
   
 0.998
rcsC
Sensor protein rcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 0.976
c0365
Hypothetical protein.
     
  0.900
rcsF
Protein rcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
      
 0.899
barA
Sensor protein barA; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity).
  
 
 0.885
arcB
Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574.
 
 
 0.816
evgS
Sensor protein evgS precursor; Escherichia coli K-12 ortholog: b2370; Escherichia coli O157:H7 ortholog: z3632.
  
 
 0.807
bglJ
Transcriptional activator protein bglJ; Escherichia coli K-12 ortholog: b4366; Escherichia coli O157:H7 ortholog: z5967.
  
 
 
0.801
torS
Sensor protein torS; Escherichia coli K-12 ortholog: b0993; Escherichia coli O157:H7 ortholog: z1410.
 
 
 0.749
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.