node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apaG | apaH | b0050 | b0049 | Protein associated with Co2+ and Mg2+ efflux. | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.994 |
apaG | kefC | b0050 | b0047 | Protein associated with Co2+ and Mg2+ efflux. | Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Can also export rubidium, lithium and sodium. | 0.532 |
apaG | lptD | b0050 | b0054 | Protein associated with Co2+ and Mg2+ efflux. | LPS assembly OM complex LptDE, beta-barrel component; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance. | 0.698 |
apaG | pdxA | b0050 | b0052 | Protein associated with Co2+ and Mg2+ efflux. | 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP); Belongs to the PdxA family. | 0.943 |
apaG | rsmA | b0050 | b0051 | Protein associated with Co2+ and Mg2+ efflux. | 16S rRNA m(6)A1518, m(6)A1519 dimethyltransferase, SAM-dependent; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Has also a DNA glycosylase/AP lyase activity that removes C mispaired with oxidized T from DNA, and may play a role in protection of DNA against oxidative stress. | 0.992 |
apaG | surA | b0050 | b0053 | Protein associated with Co2+ and Mg2+ efflux. | Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins, such as OmpA, OmpF and LamB. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane- associated steps of protein maturation. Essential for the survival of E.coli in stationary phase. Required for pilus biogenesis. | 0.874 |
apaG | ybeX | b0050 | b0658 | Protein associated with Co2+ and Mg2+ efflux. | Putative ion transport; Plays a role in the transport of magnesium and cobalt ions. | 0.673 |
apaG | ybjS | b0050 | b0868 | Protein associated with Co2+ and Mg2+ efflux. | Putative NAD(P)H-dependent oxidoreductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.528 |
apaG | yjbT | b0050 | b4620 | Protein associated with Co2+ and Mg2+ efflux. | Putative periplasmic protein; Belongs to the YjbT family. | 0.541 |
apaG | yjiM | b0050 | b4335 | Protein associated with Co2+ and Mg2+ efflux. | Putative 2-hydroxyglutaryl-CoA dehydratase; Belongs to the FldB/FldC dehydratase alpha/beta subunit family. | 0.529 |
apaH | apaG | b0049 | b0050 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Protein associated with Co2+ and Mg2+ efflux. | 0.994 |
apaH | kefC | b0049 | b0047 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Can also export rubidium, lithium and sodium. | 0.655 |
apaH | lptD | b0049 | b0054 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | LPS assembly OM complex LptDE, beta-barrel component; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance. | 0.772 |
apaH | pdxA | b0049 | b0052 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP); Belongs to the PdxA family. | 0.938 |
apaH | rsmA | b0049 | b0051 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 16S rRNA m(6)A1518, m(6)A1519 dimethyltransferase, SAM-dependent; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Has also a DNA glycosylase/AP lyase activity that removes C mispaired with oxidized T from DNA, and may play a role in protection of DNA against oxidative stress. | 0.969 |
apaH | surA | b0049 | b0053 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins, such as OmpA, OmpF and LamB. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane- associated steps of protein maturation. Essential for the survival of E.coli in stationary phase. Required for pilus biogenesis. | 0.943 |
kefC | apaG | b0047 | b0050 | Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Can also export rubidium, lithium and sodium. | Protein associated with Co2+ and Mg2+ efflux. | 0.532 |
kefC | apaH | b0047 | b0049 | Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Can also export rubidium, lithium and sodium. | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.655 |
lptD | apaG | b0054 | b0050 | LPS assembly OM complex LptDE, beta-barrel component; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance. | Protein associated with Co2+ and Mg2+ efflux. | 0.698 |
lptD | apaH | b0054 | b0049 | LPS assembly OM complex LptDE, beta-barrel component; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance. | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.772 |