STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yafCPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (304 aa)    
Predicted Functional Partners:
xapR
Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine.
  
     0.756
lrhA
Transcriptional repressor of flagellar, motility and chemotaxis genes; Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon.
  
     0.720
yafD
Endo/exonuclease/phosphatase family protein.
  
  
 0.683
ybdO
Putative transcriptional regulator LYSR-type; Protein involved in transcription and regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family.
  
   
 0.528
yfhH
Putative DNA-binding transcriptional regulator.
    
 
 0.493
yafE
Putative S-adenosyl-L-methionine-dependent methyltransferase; Putative biotin synthesis protein; Protein involved in biotin biosynthetic process; Belongs to the methyltransferase superfamily.
  
    0.468
yeeY
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
     0.452
ynfL
Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family.
  
   
0.436
yiaU
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
   
0.433
yeiE
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
   
0.432
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.