STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yafYLipoprotein, inner membrane; When overproduced strongly induces degP through the activation of the two-component envelope stress response system CpxA/CpxR ; To E.coli YfjS. (147 aa)    
Predicted Functional Partners:
ykfB
CP4-6 prophage; uncharacterized protein; To E.coli YfjT.
  
    0.907
ykfF
CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family.
  
    0.667
nlpE
Lipoprotein involved with copper homeostasis and adhesion; Involved in copper homeostasis, could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes. Required for efficient binding of stationary phase cells to hydrophobic surfaces, part of the process of biofilm formation. Functions during envelope stress responses; when overproduced induces degP through the activation of the two-component envelope stress response system CpxA/CpxR. DegP induction seems to require membrane anchoring of this protein. Structural changes and/or interaction of the CXXC m [...]
      
 0.600
yafX
CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family.
  
    0.475
ykfA
CP4-6 prophage; Putative GTP-binding protein; To E.coli YfjP and YeeP.
  
    0.432
ykfG
CP4-6 prophage; Putative DNA repair protein; Belongs to the UPF0758 family.
  
    0.407
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.