node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aldA | fucO | b1415 | b2799 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | 0.983 |
aldA | ghrB | b1415 | b3553 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.939 |
aldA | xylA | b1415 | b3565 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.402 |
aldA | xylB | b1415 | b3564 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Xylulokinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate. Also catalyzes the phosphorylation of 1- deoxy-D-xylulose to 1-deoxy-D-xylulose 5-phosphate, with lower efficiency. Can also use D-ribulose, xylitol and D- arabitol, but D-xylulose is preferred over the other substrates. Has a weak substrate-independent Mg-ATP-hydrolyzing activity ; Belongs to the FGGY kinase family. | 0.527 |
aldA | yagE | b1415 | b0268 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | 2-keto-3-deoxy gluconate (KDG) aldolase; Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde. May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin ; Belongs to the DapA family. | 0.819 |
aldA | yagF | b1415 | b0269 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | CP4-6 prophage; Catalyzes the dehydration of D-xylonic acid to form 2- dehydro-3-deoxy-D-pentonate; Belongs to the IlvD/Edd family. | 0.616 |
aldA | yjhG | b1415 | b4297 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Putative dehydratase; Catalyzes the dehydration of D-xylonic acid to form 2- dehydro-3-deoxy-D-pentonate. | 0.634 |
aldA | yjhH | b1415 | b4298 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Putative lyase/synthase; Functions as a 2-dehydro-3-deoxy-D-pentonate aldolase. Belongs to the DapA family. | 0.754 |
dapB | yagE | b0031 | b0268 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and NADPH as a reductant, with NADH being twice as effective as NADPH. Belongs to the DapB family. | 2-keto-3-deoxy gluconate (KDG) aldolase; Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde. May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin ; Belongs to the DapA family. | 0.858 |
dapB | yjhH | b0031 | b4298 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and NADPH as a reductant, with NADH being twice as effective as NADPH. Belongs to the DapB family. | Putative lyase/synthase; Functions as a 2-dehydro-3-deoxy-D-pentonate aldolase. Belongs to the DapA family. | 0.856 |
fucO | aldA | b2799 | b1415 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | 0.983 |
fucO | xylA | b2799 | b3565 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.555 |
fucO | xylB | b2799 | b3564 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | Xylulokinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate. Also catalyzes the phosphorylation of 1- deoxy-D-xylulose to 1-deoxy-D-xylulose 5-phosphate, with lower efficiency. Can also use D-ribulose, xylitol and D- arabitol, but D-xylulose is preferred over the other substrates. Has a weak substrate-independent Mg-ATP-hydrolyzing activity ; Belongs to the FGGY kinase family. | 0.522 |
fucO | yagE | b2799 | b0268 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | 2-keto-3-deoxy gluconate (KDG) aldolase; Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde. May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin ; Belongs to the DapA family. | 0.808 |
fucO | yagF | b2799 | b0269 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | CP4-6 prophage; Catalyzes the dehydration of D-xylonic acid to form 2- dehydro-3-deoxy-D-pentonate; Belongs to the IlvD/Edd family. | 0.568 |
fucO | yjhG | b2799 | b4297 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | Putative dehydratase; Catalyzes the dehydration of D-xylonic acid to form 2- dehydro-3-deoxy-D-pentonate. | 0.560 |
fucO | yjhH | b2799 | b4298 | L-1,2-propanediol oxidoreductase; Protein involved in carbohydrate catabolic process and glycolate metabolic process; Belongs to the iron-containing alcohol dehydrogenase family. | Putative lyase/synthase; Functions as a 2-dehydro-3-deoxy-D-pentonate aldolase. Belongs to the DapA family. | 0.795 |
ghrB | aldA | b3553 | b1415 | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | 0.939 |
ghrB | xylA | b3553 | b3565 | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.507 |
ghrB | yagE | b3553 | b0268 | Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2- keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D- fructose and L-sorbose. Activity with NAD is very low; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 2-keto-3-deoxy gluconate (KDG) aldolase; Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde. May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin ; Belongs to the DapA family. | 0.789 |