node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bluF | yagK | b1163 | b0277 | Anti-repressor for YcgE, blue light-responsive; Binds to and releases the BluR repressor from its bound DNA target in a blue light-dependent (470 nm) fashion. A shift to low temperature also triggers a BluF-mediated relief of repression by BluR, suggesting BluF may serve as a thermometer. Blue light may act to increase the affinity of BluF for BluR, allowing it to be released from its operator. The protein has a reversible photocycle, and undergoes structural changes, probably in the EAL domain, in response to light. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.509 |
bluF | ycgZ | b1163 | b1164 | Anti-repressor for YcgE, blue light-responsive; Binds to and releases the BluR repressor from its bound DNA target in a blue light-dependent (470 nm) fashion. A shift to low temperature also triggers a BluF-mediated relief of repression by BluR, suggesting BluF may serve as a thermometer. Blue light may act to increase the affinity of BluF for BluR, allowing it to be released from its operator. The protein has a reversible photocycle, and undergoes structural changes, probably in the EAL domain, in response to light. | RcsB connector protein for regulation of biofilm and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component. | 0.762 |
gtrS | yagK | b2352 | b0277 | Serotype-specific glucosyl transferase, CPS-53 (KpLE1) prophage; Putative ligase. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.624 |
rcdA | yagK | b0846 | b0277 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.480 |
rcdA | ybjJ | b0846 | b0845 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | 0.963 |
sxy | yagK | b0959 | b0277 | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.457 |
yagK | bluF | b0277 | b1163 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | Anti-repressor for YcgE, blue light-responsive; Binds to and releases the BluR repressor from its bound DNA target in a blue light-dependent (470 nm) fashion. A shift to low temperature also triggers a BluF-mediated relief of repression by BluR, suggesting BluF may serve as a thermometer. Blue light may act to increase the affinity of BluF for BluR, allowing it to be released from its operator. The protein has a reversible photocycle, and undergoes structural changes, probably in the EAL domain, in response to light. | 0.509 |
yagK | gtrS | b0277 | b2352 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | Serotype-specific glucosyl transferase, CPS-53 (KpLE1) prophage; Putative ligase. | 0.624 |
yagK | rcdA | b0277 | b0846 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | 0.480 |
yagK | sxy | b0277 | b0959 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | 0.457 |
yagK | yagL | b0277 | b0278 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | CP4-6 prophage; DNA-binding protein. | 0.501 |
yagK | yagM | b0277 | b0279 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | CP4-6 prophage; uncharacterized protein. | 0.569 |
yagK | ybjJ | b0277 | b0845 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | 0.621 |
yagK | ycgZ | b0277 | b1164 | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | RcsB connector protein for regulation of biofilm and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component. | 0.510 |
yagL | yagK | b0278 | b0277 | CP4-6 prophage; DNA-binding protein. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.501 |
yagL | yagM | b0278 | b0279 | CP4-6 prophage; DNA-binding protein. | CP4-6 prophage; uncharacterized protein. | 0.947 |
yagM | yagK | b0279 | b0277 | CP4-6 prophage; uncharacterized protein. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.569 |
yagM | yagL | b0279 | b0278 | CP4-6 prophage; uncharacterized protein. | CP4-6 prophage; DNA-binding protein. | 0.947 |
ybjJ | rcdA | b0845 | b0846 | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | 0.963 |
ybjJ | yagK | b0845 | b0277 | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | CP4-6 prophage; uncharacterized protein;Phage or Prophage Related; To E.coli YfjJ. | 0.621 |