STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yahNAmino acid exporter for proline, lysine, glutamate, homoserine; Putative cytochrome subunit of dehydrogenase. (223 aa)    
Predicted Functional Partners:
argO
Arginine transporter; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine. May also be involved in the export of canavanine (a plant-derived antimetabolite).
  
   
 0.875
yddG
Aromatic amino acid exporter YddG; Probable efflux pump. Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan; Belongs to the drug/metabolite transporter (DMT) superfamily. Aromatic amino acid/paraquat exporter (ArAA/P-E) (TC 2.A.7.17) family.
      
 0.872
ybjE
Putative transporter; Mediates export of lysine; Belongs to the LysO family.
   
  
 0.733
alaE
Alanine exporter, alanine-inducible, stress-responsive; Exports L-alanine; Belongs to the AlaE exporter family.
   
  
 0.732
argP
HTH-type transcriptional regulator ArgP; Controls the transcription of genes involved in arginine and lysine metabolism. Activates transcription of several genes, including argO, lysP, lysC, asd, dapB, dapD, lysA, gdhA and argK. Acts by binding directly to their promoter or control region. ArgP dimer by itself is able to bind the argO promoter-operator region to form a binary complex, but the formation of a ternary complex with RNA polymerase is greatly stimulated only in presence of a coeffector. Both arginine and lysine are coeffectors at the argO promoter, but only arginine is compe [...]
  
   
 0.679
yjeH
Putative transporter; Catalyzes the efflux of L-methionine. Can also export L- leucine, L-isoleucine and L-valine. Activity is dependent on electrochemical potential.
  
  
 0.537
yahO
Periplasmic protein, function unknown, YhcN family.
       0.525
rhtB
Homoserine, homoserine lactone and S-methyl-methionine efflux pump; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family.
  
   
0.525
ytfF
DMT transporter family inner membrane protein; Putative transmembrane subunit.
   
  
 0.510
abgT
P-aminobenzoyl-glutamate transporter; Essential for aminobenzoyl-glutamate utilization. It catalyzes the concentration-dependent uptake of p-aminobenzoyl- glutamate (PABA-GLU) into the cell and allows accumulation of PABA-GLU to a concentration enabling AbgAB to catalyze cleavage into p- aminobenzoate and glutamate. It seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate. May actually serve physiologically as a transporter for some other molecule, perhaps a dipeptide, and that it transports p-aminobenzoyl-glutamate as a secondary activity. The physiological ro [...]
      
 0.451
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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