node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
can | cynS | b0126 | b0340 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | 0.964 |
can | cynT | b0126 | b0339 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.943 |
can | nirC | b0126 | b3367 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Nitrite transporter; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane. Is up to 10-fold more active than NarK or NarU in nitrite uptake for subsequent reduction in the cytoplasm by the NirB/NirD nitrite reductase; Belongs to the FNT transporter (TC 2.A.44) family. | 0.472 |
cmtA | cynS | b2933 | b0340 | Putative mannitol-specific PTS IIB and IIC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | 0.504 |
cynR | cynS | b0338 | b0340 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | 0.765 |
cynR | cynT | b0338 | b0339 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.893 |
cynR | cynX | b0338 | b0341 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | Putative cyanate transporter; This protein is part of an active transport system that transports exogenous cyanate into E.coli cells; Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family. | 0.701 |
cynS | can | b0340 | b0126 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.964 |
cynS | cmtA | b0340 | b2933 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative mannitol-specific PTS IIB and IIC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. | 0.504 |
cynS | cynR | b0340 | b0338 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | 0.765 |
cynS | cynT | b0340 | b0339 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.998 |
cynS | cynX | b0340 | b0341 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative cyanate transporter; This protein is part of an active transport system that transports exogenous cyanate into E.coli cells; Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family. | 0.969 |
cynS | nirC | b0340 | b3367 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Nitrite transporter; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane. Is up to 10-fold more active than NarK or NarU in nitrite uptake for subsequent reduction in the cytoplasm by the NirB/NirD nitrite reductase; Belongs to the FNT transporter (TC 2.A.44) family. | 0.469 |
cynS | yahI | b0340 | b0323 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Carbamate kinase-like protein; Putative kinase; Protein involved in arginine biosynthetic process and pyrimidine nucleotide biosynthetic process; Belongs to the carbamate kinase family. | 0.902 |
cynS | ybcF | b0340 | b0521 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative carbamate kinase; Protein involved in arginine biosynthetic process and pyrimidine nucleotide biosynthetic process. | 0.900 |
cynS | ycgM | b0340 | b1180 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative isomerase; Belongs to the FAH family. | 0.474 |
cynS | yqeA | b0340 | b2874 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative kinase; Belongs to the carbamate kinase family. | 0.900 |
cynT | can | b0339 | b0126 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.943 |
cynT | cynR | b0339 | b0338 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | 0.893 |
cynT | cynS | b0339 | b0340 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | 0.998 |