STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybcMDLP12 prophage; Putative ARAC-type regulatory protein. (265 aa)    
Predicted Functional Partners:
ybcL
Inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; UPF0098 family secreted protein.
 
  
 0.949
gadW
Transcriptional activator of gadA and gadBC; Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters.
  
  
 0.768
ykfM
Lethality reduction protein, putative inner membrane protein.
      
 0.740
envY
Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB.
  
     0.726
adiY
Adi system transcriptional activator; Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription.
  
     0.641
gadX
Acid resistance regulon transcriptional activator; Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW.
  
    0.629
ycaN
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
  
  
 0.607
ycjW
Putative LACI-type transcriptional regulator; Protein involved in transcription repressor activity and transcription.
   
  
 0.547
yadC
Putative fimbrial-like adhesin protein; Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.
   
  
 0.533
yjhI
Putative regulator; Protein involved in transcription repressor activity and transcription.
   
  
 0.527
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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