STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phePPhenylalanine transporter; Permease that is involved in the transport across the cytoplasmic membrane of phenylalanine; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (458 aa)    
Predicted Functional Partners:
lacY
Lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose. The substrate specificity is directed toward the galactopyranosyl moiety of the substrate.
    
 
 0.875
tyrP
Tyrosine transporter; Involved in transporting tyrosine across the cytoplasmic membrane.
      
 0.621
cusA
Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
    0.546
tnaB
Tryptophan transporter of low affinity; Involved in tryptophan transport across the cytoplasmic membrane. Plays a role in transporting tryptophan which is to be used catabolically.
      
 0.544
yqcE
Putative MFS transporter, inner membrane protein; Putative transport protein.
   
  
 0.529
ppiA
Peptidyl-prolyl cis-trans isomerase A (rotamase A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
      
 0.523
yijD
DUF1422 family inner membrane protein.
      
 0.519
cusB
Copper/silver efflux system, membrane fusion protein; Part of a cation efflux system that mediates resistance to copper and silver.
  
    0.515
pssA
Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process.
   
  
 0.501
yaaJ
Putative transporter; Inner membrane transport protein.
      
 0.491
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.