node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acs | aldA | b4069 | b1415 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | 0.889 |
acs | cstA | b4069 | b0598 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | 0.589 |
acs | mglB | b4069 | b2150 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Methyl-galactoside transporter subunit; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. | 0.693 |
acs | putP | b4069 | b1015 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. | 0.546 |
aldA | acs | b1415 | b4069 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.889 |
aldA | cstA | b1415 | b0598 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | 0.683 |
aldA | mglB | b1415 | b2150 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Methyl-galactoside transporter subunit; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. | 0.811 |
aldA | putP | b1415 | b1015 | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. | 0.546 |
csrA | cstA | b2696 | b0598 | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability, initially identified for its effects on central carbon metabolism. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Binds to the 5'-UTR of mRNA to repress or activate translation; 2 binding sites on the homodimer can bridge 2 sites within target RNA (By similarity). Exerts reciprocal effects on [...] | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | 0.685 |
csrA | glgC | b2696 | b3430 | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability, initially identified for its effects on central carbon metabolism. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Binds to the 5'-UTR of mRNA to repress or activate translation; 2 binding sites on the homodimer can bridge 2 sites within target RNA (By similarity). Exerts reciprocal effects on [...] | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.914 |
cstA | acs | b0598 | b4069 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.589 |
cstA | aldA | b0598 | b1415 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Aldehyde dehydrogenase A, NAD-linked; Acts on lactaldehyde as well as other aldehydes. | 0.683 |
cstA | csrA | b0598 | b2696 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability, initially identified for its effects on central carbon metabolism. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Binds to the 5'-UTR of mRNA to repress or activate translation; 2 binding sites on the homodimer can bridge 2 sites within target RNA (By similarity). Exerts reciprocal effects on [...] | 0.685 |
cstA | glgC | b0598 | b3430 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.674 |
cstA | mglB | b0598 | b2150 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Methyl-galactoside transporter subunit; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. | 0.687 |
cstA | putP | b0598 | b1015 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. | 0.729 |
cstA | ybdD | b0598 | b4512 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | DUF466 family protein; To E.coli YjiX. | 0.937 |
cstA | yehT | b0598 | b2125 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Putative response regulator in two-component system withYehU; Member of the two-component regulatory system BtsS/BtsR, which is part of a nutrient-sensing regulatory network composed of BtsS/BtsR, the low-affinity pyruvate signaling system YpdA/YpdB and their respective target proteins, BtsT and YhjX. Responds to depletion of nutrients, specifically serine, and the concomitant presence of extracellular pyruvate. BtsR regulates expression of btsT by binding to its promoter region. Activation of the BtsS/BtsR signaling cascade also suppresses YpdA/YpdB-mediated yhjX induction. | 0.624 |
cstA | yehU | b0598 | b2126 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | Inner membrane putative sensory kinase in two-component system with YehT; Member of the two-component regulatory system BtsS/BtsR, which is part of a nutrient-sensing regulatory network composed of BtsS/BtsR, the low-affinity pyruvate signaling system YpdA/YpdB and their respective target proteins, BtsT and YhjX. Responds to depletion of nutrients, specifically serine, and the concomitant presence of extracellular pyruvate. BtsS is a high-affinity receptor for extracellular pyruvate that activates BtsR by phosphorylation. Activation of the BtsS/BtsR signaling cascade also suppresses Yp [...] | 0.707 |
cstA | yjiX | b0598 | b4353 | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. | DUF466 family protein; To E.coli YbdD. | 0.854 |