STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhCacyl-CoA thioesterase, lipoprotein; Putative thioesterase. Does not bind pectin, and has no pectinesterase activity; Belongs to the pectinesterase family. (427 aa)    
Predicted Functional Partners:
ybhB
Kinase inhibitor homolog, UPF0098 family; Belongs to the UPF0098 family.
     
 0.942
rna
Ribonuclease I; One of the few RNases that cleaves the phosphodiester bond between any two nucleotide. Shows a preference for cytidylic or guanylic acid.
  
     0.765
wcaC
Putative glycosyl transferase; Protein involved in colanic acid biosynthetic process.
  
     0.735
sbmC
DNA gyrase inhibitor; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. Protects cells against the natural plasmid-encoded toxins microcin B17 (MccB17) and CcdB, and synthetic quinolones. Can also protect cells against alkylating agents that act independently of DNA gyrase, suggesting a more general role in protectin [...]
  
   
 0.731
bglJ
Bgl operon transcriptional activator; A crytic transcriptional activator. When its expression is induced it relieves H-NS repression of the bgl operon. Acts independently of transcription factor LeuO.
  
    0.727
ybfP
Lipoprotein; Putative pectinase.
      
 0.675
yfeO
Putative ion channel protein.
  
     0.665
ybiO
Mechanosensitive channel protein, intermediate conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family.
  
     0.662
nudI
Nucleoside triphosphatase; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
  
     0.603
yieL
Putative xylanase; Protein involved in carbohydrate catabolic process.
  
     0.603
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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