node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
coaA | ybjN | b3974 | b0853 | Pantothenate kinase; Protein involved in coenzyme A biosynthetic process; Belongs to the prokaryotic pantothenate kinase family. | Negative regulator of motility; Putative sensory transduction regulator. | 0.514 |
nfsA | rimK | b0851 | b0852 | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | 0.884 |
nfsA | ybjC | b0851 | b0850 | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | DUF1418 family protein. | 0.985 |
nfsA | ybjN | b0851 | b0853 | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | Negative regulator of motility; Putative sensory transduction regulator. | 0.743 |
potF | ybjN | b0854 | b0853 | Putrescine ABC transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine. Polyamine binding protein. Belongs to the bacterial solute-binding protein PotD/PotF family. | Negative regulator of motility; Putative sensory transduction regulator. | 0.410 |
rimK | nfsA | b0852 | b0851 | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | 0.884 |
rimK | ybjC | b0852 | b0850 | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | DUF1418 family protein. | 0.899 |
rimK | ybjN | b0852 | b0853 | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | Negative regulator of motility; Putative sensory transduction regulator. | 0.958 |
ybjC | nfsA | b0850 | b0851 | DUF1418 family protein. | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | 0.985 |
ybjC | rimK | b0850 | b0852 | DUF1418 family protein. | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | 0.899 |
ybjC | ybjN | b0850 | b0853 | DUF1418 family protein. | Negative regulator of motility; Putative sensory transduction regulator. | 0.736 |
ybjN | coaA | b0853 | b3974 | Negative regulator of motility; Putative sensory transduction regulator. | Pantothenate kinase; Protein involved in coenzyme A biosynthetic process; Belongs to the prokaryotic pantothenate kinase family. | 0.514 |
ybjN | nfsA | b0853 | b0851 | Negative regulator of motility; Putative sensory transduction regulator. | Nitroreductase A, NADPH-dependent, FMN-dependent; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major oxygen-insensitive nitroreductase in E.coli. | 0.743 |
ybjN | potF | b0853 | b0854 | Negative regulator of motility; Putative sensory transduction regulator. | Putrescine ABC transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine. Polyamine binding protein. Belongs to the bacterial solute-binding protein PotD/PotF family. | 0.410 |
ybjN | rimK | b0853 | b0852 | Negative regulator of motility; Putative sensory transduction regulator. | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. | 0.958 |
ybjN | ybjC | b0853 | b0850 | Negative regulator of motility; Putative sensory transduction regulator. | DUF1418 family protein. | 0.736 |
ybjN | yigZ | b0853 | b3848 | Negative regulator of motility; Putative sensory transduction regulator. | UPF0029 family protein; Protein involved in translation; Belongs to the IMPACT family. | 0.471 |
ybjN | ypjF | b0853 | b2646 | Negative regulator of motility; Putative sensory transduction regulator. | CP4-57 prophage; Toxic component of a type IV toxin-antitoxin (TA) system. Acts as a dual toxin inhibitor that blocks cell division and cell elongation in genetically separable interactions with FtsZ and MreB. Overexpression results in inhibition of growth in liquid cultures. Overexpression leads to formation of lemon-shaped cells; inactivated by overexpression of cognate antitoxin YfjZ but not when the 2 genes are coexpressed from the same plasmid. Also neutralized by overexpression of non-cognate antitoxins YafW and CbeA. | 0.499 |
yigZ | ybjN | b3848 | b0853 | UPF0029 family protein; Protein involved in translation; Belongs to the IMPACT family. | Negative regulator of motility; Putative sensory transduction regulator. | 0.471 |
ypjF | ybjN | b2646 | b0853 | CP4-57 prophage; Toxic component of a type IV toxin-antitoxin (TA) system. Acts as a dual toxin inhibitor that blocks cell division and cell elongation in genetically separable interactions with FtsZ and MreB. Overexpression results in inhibition of growth in liquid cultures. Overexpression leads to formation of lemon-shaped cells; inactivated by overexpression of cognate antitoxin YfjZ but not when the 2 genes are coexpressed from the same plasmid. Also neutralized by overexpression of non-cognate antitoxins YafW and CbeA. | Negative regulator of motility; Putative sensory transduction regulator. | 0.499 |