node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amiB | amiC | b4169 | b2817 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.944 |
amiB | amiD | b4169 | b0867 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | 0.816 |
amiB | rlpA | b4169 | b0633 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.586 |
amiB | slt | b4169 | b4392 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.457 |
amiC | amiB | b2817 | b4169 | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | 0.944 |
amiC | amiD | b2817 | b0867 | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | 0.823 |
amiC | rlpA | b2817 | b0633 | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.582 |
amiC | slt | b2817 | b4392 | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.513 |
amiD | amiB | b0867 | b4169 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. | 0.816 |
amiD | amiC | b0867 | b2817 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.823 |
amiD | ampG | b0867 | b0433 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 0.917 |
amiD | ldcA | b0867 | b1192 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Murein tetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso-Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc-anhMurNAc-tetrapeptide. Does not act on murein sacculi or cross-linked muropeptides. The tripeptides produced by the LcdA reaction can then be reused as peptidoglycan building blocks; LcdA is thereby involved in murein recycling. Is also essen [...] | 0.917 |
amiD | nagZ | b0867 | b1107 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Beta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides. | 0.794 |
amiD | rlpA | b0867 | b0633 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.640 |
amiD | slt | b0867 | b4392 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.730 |
amiD | thiE | b0867 | b3993 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Thiamine phosphate synthase (thiamine phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.881 |
amiD | ybjQ | b0867 | b0866 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | UPF0145 family protein. | 0.983 |
amiD | yfeW | b0867 | b2430 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | Penicillin binding protein PBP4B; Penicillin-binding protein. Has low DD-carboxypeptidase activity; Belongs to the peptidase S12 family. YfeW subfamily. | 0.905 |
ampG | amiD | b0433 | b0867 | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. | 0.917 |
ampG | ldcA | b0433 | b1192 | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | Murein tetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso-Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc-anhMurNAc-tetrapeptide. Does not act on murein sacculi or cross-linked muropeptides. The tripeptides produced by the LcdA reaction can then be reused as peptidoglycan building blocks; LcdA is thereby involved in murein recycling. Is also essen [...] | 0.853 |