node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ftsK | ycaI | b0890 | b0913 | DNA translocase at septal ring sorting daughter chromsomes; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (K [...] | ComEC family inner membrane protein. | 0.662 |
gntX | hofC | b3413 | b0106 | DNA catabolic protein; Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism ; Belongs to the ComF/GntX family. | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | 0.443 |
gntX | smf | b3413 | b4473 | DNA catabolic protein; Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism ; Belongs to the ComF/GntX family. | DNA recombination-mediator A family protein; Partially complements natural chromosomal DNA transformation defect of an H.influenzae dprA disruption mutant. May help load RecA onto ssDNA (By similarity). Belongs to the DprA/Smf family. | 0.953 |
gntX | ycaI | b3413 | b0913 | DNA catabolic protein; Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism ; Belongs to the ComF/GntX family. | ComEC family inner membrane protein. | 0.806 |
gspO | hofC | b3335 | b0106 | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | 0.884 |
gspO | hofQ | b3335 | b3391 | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | DNA catabolic putative fimbrial transporter; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane. | 0.781 |
gspO | smf | b3335 | b4473 | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | DNA recombination-mediator A family protein; Partially complements natural chromosomal DNA transformation defect of an H.influenzae dprA disruption mutant. May help load RecA onto ssDNA (By similarity). Belongs to the DprA/Smf family. | 0.646 |
gspO | ycaI | b3335 | b0913 | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | ComEC family inner membrane protein. | 0.685 |
hofC | gntX | b0106 | b3413 | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | DNA catabolic protein; Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism ; Belongs to the ComF/GntX family. | 0.443 |
hofC | gspO | b0106 | b3335 | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.884 |
hofC | hofQ | b0106 | b3391 | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | DNA catabolic putative fimbrial transporter; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane. | 0.958 |
hofC | smf | b0106 | b4473 | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | DNA recombination-mediator A family protein; Partially complements natural chromosomal DNA transformation defect of an H.influenzae dprA disruption mutant. May help load RecA onto ssDNA (By similarity). Belongs to the DprA/Smf family. | 0.465 |
hofC | ycaI | b0106 | b0913 | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | ComEC family inner membrane protein. | 0.679 |
hofQ | gspO | b3391 | b3335 | DNA catabolic putative fimbrial transporter; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane. | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.781 |
hofQ | hofC | b3391 | b0106 | DNA catabolic putative fimbrial transporter; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane. | Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake. | 0.958 |
hofQ | ycaI | b3391 | b0913 | DNA catabolic putative fimbrial transporter; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane. | ComEC family inner membrane protein. | 0.807 |
lpxK | msbA | b0915 | b0914 | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipid ABC transporter permease/ATPase; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. | 0.991 |
lpxK | ycaI | b0915 | b0913 | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | ComEC family inner membrane protein. | 0.853 |
lpxK | ycaQ | b0915 | b0916 | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | DUF1006 family protein with C-terminal wHTH domain. | 0.791 |
msbA | lpxK | b0914 | b0915 | Lipid ABC transporter permease/ATPase; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.991 |