node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
efeB | phoH | b1019 | b1020 | Deferrrochelatase, periplasmic; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Also displays peroxidase activity on guaiacol in vitro. | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | 0.598 |
gsiA | phoH | b0829 | b1020 | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | 0.569 |
gsiA | pstA | b0829 | b3726 | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.540 |
gsiA | pstC | b0829 | b3727 | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.540 |
gsiA | pstS | b0829 | b3728 | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | Phosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.565 |
mazG | phoH | b2781 | b1020 | Nucleoside triphosphate pyrophosphohydrolase; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the type II MazE-MazF toxin-antitoxin (TA) system which mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA. Belongs to the nucleoside trip [...] | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | 0.819 |
phoH | efeB | b1020 | b1019 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Deferrrochelatase, periplasmic; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Also displays peroxidase activity on guaiacol in vitro. | 0.598 |
phoH | gsiA | b1020 | b0829 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | 0.569 |
phoH | mazG | b1020 | b2781 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Nucleoside triphosphate pyrophosphohydrolase; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the type II MazE-MazF toxin-antitoxin (TA) system which mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA. Belongs to the nucleoside trip [...] | 0.819 |
phoH | psiE | b1020 | b4030 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Phosphate starvation inducible protein; Belongs to the PsiE family. | 0.812 |
phoH | pstA | b1020 | b3726 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.641 |
phoH | pstC | b1020 | b3727 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.609 |
phoH | pstS | b1020 | b3728 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Phosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.600 |
phoH | recO | b1020 | b2565 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | Gap repair protein; Involved in DNA repair and RecF pathway recombination; Belongs to the RecO family. | 0.648 |
phoH | tadA | b1020 | b2559 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2). Essential for cell viability. Belongs to the cytidine and deoxycytidylate deaminase family. | 0.651 |
phoH | ybeY | b1020 | b0659 | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | ssRNA-specific endoribonuclease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. Acts together with the RNase R to eliminate defective 70S ribosomes, but not properly matured 70S ribosomes or individual subunits, by a process mediated specifically by the 30S ribosomal subunit. Involved in the processing of 16S, 23S and 5S rRNAs, with a particularly strong effect on maturation at both the 5'- and 3'- ends of 16S rRNA as well as maturation of the 5'-end of 23S and 5S rRNAs. | 0.893 |
psiE | phoH | b4030 | b1020 | Phosphate starvation inducible protein; Belongs to the PsiE family. | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | 0.812 |
psiE | pstS | b4030 | b3728 | Phosphate starvation inducible protein; Belongs to the PsiE family. | Phosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.433 |
pstA | gsiA | b3726 | b0829 | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. | 0.540 |
pstA | phoH | b3726 | b1020 | Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. | 0.641 |