node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ghrA | ycdX | b1033 | b1034 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.911 |
ghrA | ycdY | b1033 | b1035 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.812 |
ghrA | ycdZ | b1033 | b1036 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | DUF1097 family inner membrane protein. | 0.690 |
hisB | hisI | b2022 | b2026 | Imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase; Protein involved in histidine biosynthetic process. | Phosphoribosyl-amp cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; Protein involved in histidine biosynthetic process; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
hisB | ycdX | b2022 | b1034 | Imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase; Protein involved in histidine biosynthetic process. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.538 |
hisI | hisB | b2026 | b2022 | Phosphoribosyl-amp cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; Protein involved in histidine biosynthetic process; In the C-terminal section; belongs to the PRA-PH family. | Imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase; Protein involved in histidine biosynthetic process. | 0.999 |
hisI | ycdX | b2026 | b1034 | Phosphoribosyl-amp cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; Protein involved in histidine biosynthetic process; In the C-terminal section; belongs to the PRA-PH family. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.651 |
purU | ycdX | b1232 | b1034 | Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). Provides the major source of formate for the PurT-dependent synthesis of 5'- phosphoribosyl-N-formylglycinamide (FGAR) during aerobic growth. Has a role in regulating the one-carbon pool. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.560 |
rhmR | wecD | b2248 | b3790 | Putative DNA-binding transcriptional regulator for the rhm operon; Putative regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.400 |
rhmR | ycdX | b2248 | b1034 | Putative DNA-binding transcriptional regulator for the rhm operon; Putative regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.566 |
torD | ycdX | b0998 | b1034 | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.545 |
torD | ycdY | b0998 | b1035 | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.786 |
wecD | rhmR | b3790 | b2248 | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Putative DNA-binding transcriptional regulator for the rhm operon; Putative regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.400 |
wecD | ycdX | b3790 | b1034 | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.542 |
wecD | ycdY | b3790 | b1035 | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.713 |
ycdX | ghrA | b1034 | b1033 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | 0.911 |
ycdX | hisB | b1034 | b2022 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase; Protein involved in histidine biosynthetic process. | 0.538 |
ycdX | hisI | b1034 | b2026 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Phosphoribosyl-amp cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; Protein involved in histidine biosynthetic process; In the C-terminal section; belongs to the PRA-PH family. | 0.651 |
ycdX | purU | b1034 | b1232 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). Provides the major source of formate for the PurT-dependent synthesis of 5'- phosphoribosyl-N-formylglycinamide (FGAR) during aerobic growth. Has a role in regulating the one-carbon pool. | 0.560 |
ycdX | rhmR | b1034 | b2248 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Putative DNA-binding transcriptional regulator for the rhm operon; Putative regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.566 |