STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msyBMulticopy suppressor of secY and secA; Could participate in the normal pathway of protein export. (124 aa)    
Predicted Functional Partners:
ydcK
Uncharacterized protein; Putative enzyme; Not classified; Belongs to the transferase hexapeptide repeat family.
   
  
 0.912
ydiZ
Uncharacterized protein.
   
    0.869
ycaC
Putative isochorismatase family hydrolase; Protein involved in cellular amino acid catabolic process.
   
    0.859
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
    0.857
yegP
UPF0339 family protein; Belongs to the UPF0339 family. Duplicated subfamily.
   
    0.844
yeaG
Protein kinase, endogenous substrate unidentified; autokinase; Belongs to the PrkA family.
   
    0.840
yiaG
HTH_CROC1 family putative transcriptional regulator; Protein involved in regulation of transcription, DNA-dependent.
   
    0.794
wrbA
NAD(P)H:quinone oxidoreductase; It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH.
   
    0.786
yqjD
Membrane-anchored ribosome-binding protein; Upon overexpression inhibits growth.
   
    0.766
hchA
Protein/nucleic acid deglycase 1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Is able to repair glycated serum albumin, aspartate aminotransferase, [...]
   
    0.764
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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