STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yceFm(7)GTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. Belongs to the Maf family. YceF subfamily. (194 aa)    
Predicted Functional Partners:
yhcC
Putative Fe-S oxidoreductase, Radical SAM superfamily protein; In vitro, can cleave S-adenosyl-L-methionine into methionine and 5'-deoxyadenosine (AdoH); Belongs to the radical SAM superfamily.
      
 0.653
yjgA
Ribosome-associated UPF0307 family protein; Putative alpha helix protein; Protein involved in ATP-binding cassette (ABC) transporter activity.
      
 0.653
yhgF
Putative transcriptional accessory protein.
      
 0.642
rpmF
50S ribosomal subunit protein L32; Protein involved in structural constituent of ribosome and translation.
     
 0.603
yceD
DUF177 family protein; Plays a role in synthesis, processing and/or stability of 23S rRNA.
  
    0.557
yeeX
UPF0265 protein YeeX; Pseudogene, CP4-44 putative prophage remnant;Phage or Prophage Related; Belongs to the UPF0265 family.
   
  
 0.541
ybcJ
Ribosome-associated protein; Its structure and the presence of conserved basic residues indicates that it probably binds RNA.
      
 0.538
fabD
malonyl-CoA-[acyl-carrier-protein] transacylase; Belongs to the FabD family.
 
   
 0.488
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.467
yhbY
RNA binding protein associated with pre-50S ribosomal subunits.
   
  
 0.460
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.