STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycfJUncharacterized protein. (179 aa)    
Predicted Functional Partners:
ypfG
DUF1176 family protein.
   
  
 0.927
osmB
Osmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival.
   
  
 0.738
yjbE
Extracellular polysaccharide production threonine-rich protein.
   
  
 0.651
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
  
    0.642
ymgD
Uncharacterized protein YmgD; Pseudogene; putative ATP-binding component of a transport system.
   
  
 0.618
yeeA
Putative transporter, FUSC family inner membrane protein.
  
     0.618
ygaC
Uncharacterized protein.
   
  
 0.617
yegS
Phosphatidylglycerol kinase, metal-dependent; In vitro phosphorylates phosphatidylglycerol but not diacylglycerol; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
  
  
 0.607
ycfT
Inner membrane protein.
   
  
 0.553
ymgG
UPF0757 family protein.
   
  
 0.536
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.