STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cohEE14 prophage; repressor protein phage e14. (224 aa)    
Predicted Functional Partners:
ymfI
E14 prophage; uncharacterized protein.
   
  
 0.896
croE
E14 prophage; putative DNA-binding transcriptional regulator.
  
  
 0.888
mcrA
Putative 5-methylcytosine/5-hydroxymethylcytosine-specific restriction nuclease; Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG.
   
  
 0.795
ymfR
Uncharacterized protein YmfR; Pseudogene, phage terminase protein A family, e14 prophage;Phage or Prophage Related.
   
  
 0.746
intE
E14 prophage; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
 
  
 0.731
ymfJ
E14 prophage; uncharacterized protein.
  
  
 0.716
recA
DNA recombination and repair protein; Required for homologous recombination and the bypass of mutagenic DNA lesions by the SOS response. Catalyzes ATP-driven homologous pairing and strand exchange of DNA molecules necessary for DNA recombinational repair. Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single- stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. The SOS response controls an apoptotic-like death (ALD) induced (in the absence of the mazE-mazF toxin-antitoxin module) in resp [...]
  
  
 0.708
ymfL
E14 prophage; putative DNA-binding transcriptional regulator.
  
  
 0.671
dicA
Qin prophage; This protein is a repressor of division inhibition gene dicB.
   
  
 0.654
tfaP
E14 prophage; uncharacterized protein; To E.coli YfdK.
   
  
 0.650
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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