STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yciGKGG family protein; Belongs to the con-10 family. (59 aa)    
Predicted Functional Partners:
yciF
Putative structural proteins.
  
  
 0.993
yciE
Putative rubrerythrin/ferritin-like metal-binding protein.
  
  
 0.930
ybgS
Putative homeobox protein.
   
  
 0.672
mcbR
Colanic acid and biofilm gene transcriptional regulator, MqsR-controlled; Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy.
   
  
 0.659
mcbA
Colanic acid mucoidy stimulation protein; Affects biofilm formation and mucoidy.
   
  
 0.616
katE
Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.613
trpL
Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.
     
 0.595
yjbJ
Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family.
   
  
 0.570
ralR
Rac prophage; Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand. Has RAL-like activity.
      
 0.517
pheL
Leader peptide of chorismate mutase-P-prephenate dehydratase; Protein involved in L-phenylalanine biosynthetic process.
      
 0.507
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.