STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osmBOsmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival. (72 aa)    
Predicted Functional Partners:
osmC
Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family.
   
  
 0.840
spy
Periplasmic ATP-independent protein refolding chaperone, stress-induced; An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding. Binds substrate over a large region of its convex inner surface. Substrate protein folds while it is bound to chaperone. Increasing Spy flexibility increases its substrate affinity and overall chaperone activity (shown for 3 different substrates). Protects proteins in vitro against tannin inactivation; tannins have antimicrobial activity. Overexpression enhances the stability of otherwise unstable periplasmic prote [...]
   
  
 0.778
ycfJ
Uncharacterized protein.
   
  
 0.738
osmY
Salt-inducible putative ABC transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress.
  
  
 0.706
fliL
Flagellar biosynthesis protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
 
 
 0.704
bdm
Biofilm-dependent modulation protein.
   
  
 0.672
pfo
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.662
sra
Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family.
   
    0.654
yjbJ
Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family.
   
  
 0.651
ygaC
Uncharacterized protein.
   
  
 0.634
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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