node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dbpA | hrpA | b1343 | b1413 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.718 |
dbpA | rhlB | b1343 | b3780 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.403 |
dbpA | rnd | b1343 | b1804 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.454 |
dbpA | rpsA | b1343 | b0911 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 30S ribosomal subunit protein S1; Required for translation of most natural mRNAs except for leaderless mRNA. Binds mRNA upstream of the Shine- Dalgarno (SD) sequence and helps it bind to the 30S ribosomal subunit; acts as an RNA chaperone to unfold structured mRNA on the ribosome but is not essential for mRNAs with strong SDs and little 5'-UTR structure, thus it may help fine-tune which mRNAs that are translated. Unwinds dsRNA by binding to transiently formed ssRNA regions; binds about 10 nucleotides. Has a preference for polypyrimidine tracts. Negatively autoregulates its own translat [...] | 0.485 |
dbpA | rpsD | b1343 | b3296 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 30S ribosomal subunit protein S4; One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis. Binds directly to RNA polymerase; Belongs to the universal ribosomal protein uS4 family. | 0.537 |
dbpA | rpsE | b1343 | b3303 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations). The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. | 0.476 |
dbpA | rpsK | b1343 | b3297 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome (By similarity); Belongs to the universal ribosomal protein uS11 family. | 0.438 |
dbpA | srmB | b1343 | b2576 | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity. Acts before DeaD. Belongs to the DEAD box helicase family. SrmB subfamily. | 0.432 |
hrpA | dbpA | b1413 | b1343 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 0.718 |
hrpA | rhlB | b1413 | b3780 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.764 |
hrpA | rnd | b1413 | b1804 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.782 |
hrpA | rpsA | b1413 | b0911 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 30S ribosomal subunit protein S1; Required for translation of most natural mRNAs except for leaderless mRNA. Binds mRNA upstream of the Shine- Dalgarno (SD) sequence and helps it bind to the 30S ribosomal subunit; acts as an RNA chaperone to unfold structured mRNA on the ribosome but is not essential for mRNAs with strong SDs and little 5'-UTR structure, thus it may help fine-tune which mRNAs that are translated. Unwinds dsRNA by binding to transiently formed ssRNA regions; binds about 10 nucleotides. Has a preference for polypyrimidine tracts. Negatively autoregulates its own translat [...] | 0.868 |
hrpA | rpsD | b1413 | b3296 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 30S ribosomal subunit protein S4; One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis. Binds directly to RNA polymerase; Belongs to the universal ribosomal protein uS4 family. | 0.829 |
hrpA | rpsE | b1413 | b3303 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations). The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. | 0.717 |
hrpA | rpsK | b1413 | b3297 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome (By similarity); Belongs to the universal ribosomal protein uS11 family. | 0.752 |
hrpA | srmB | b1413 | b2576 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity. Acts before DeaD. Belongs to the DEAD box helicase family. SrmB subfamily. | 0.707 |
hrpA | ssb | b1413 | b4059 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. Acts as a sliding platform that migrates on DNA via reptation. SSB or its 10 C-terminal amino acids stimulates the ATPase activity of RadD. | 0.799 |
hrpA | yahD | b1413 | b0318 | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | Ankyrin repeat protein; Putative transcription factor. | 0.690 |
rhlB | dbpA | b3780 | b1343 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | ATP-dependent RNA helicase, specific for 23S rRNA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix. | 0.403 |
rhlB | hrpA | b3780 | b1413 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | Putative ATP-dependent helicase; Not yet known; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.764 |