STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhCPutative arabinose efflux transporter; Putative transport protein. (403 aa)    
Predicted Functional Partners:
ydhB
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
 
   
 0.930
yfcJ
Putative arabinose efflux transporter; Overexpression has no effect on intracellular arabinose concentrations.
   
  
 0.650
ydeA
Arabinose efflux transporter, arabinose-inducible; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
  
  
 0.584
mhpT
3-hydroxyphenylpropionic transporter; Uptake of 3-(3-hydroxyphenyl)propionate (3HPP) across the cytoplasmic membrane. Transport is driven by the proton motive force. Does not transport benzoate, 3-hydroxybenzoate or gentisate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
  
  
 0.547
ghxP
Guanine/hypoxanthine permease, high affinity; High-affinity transporter for guanine and hypoxanthine.
      
 0.524
yhhS
Putative arabinose efflux transporter; Confers high-level resistance to glyphosate when overexpressed. Overexpression has no effect on intracellular arabinose concentrations. Belongs to the major facilitator superfamily. YhhS family.
      
 0.505
iceT
Putative citrate/iron-citrate/zinc-citrate efflux transporter; Putative transport protein; Belongs to the major facilitator superfamily. TCR/Tet family.
  
   
 0.504
yebQ
Putative transport protein.
  
   
 0.503
purR
Transcriptional repressor, hypoxanthine-binding; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. In addition, it participates in the regulation or coregulation of genes involved in de novo pyrimidine nucleotide biosynthesis, salvage and uptake (pyrC, pyrD, carAB and codBA), and of several genes encoding enzymes necessary for nucleotide and polyamine biosynthesis (prsA, glyA, gcvTHP, speA, glnB). Binds to a 16-bp palindromic sequence located within the promoter region [...]
      
 0.502
hsrA
Putative multidrug or homocysteine efflux system; Putative transport protein (MFS family); high copy suppressor of RspA: relieves RspA-mediated reduction of sigma(S) levels; overexpression also reduces MetE activity; effect proposed to be via an elevation in levels of homocysteine, causing a concomitant increase in homocysteine thiolactone; overexpression has no effect on resistance to a variety of toxic compounds; overexpression has no effect on resistance to a variety of toxic compounds; Belongs to the major facilitator superfamily. EmrB family.
  
   
 0.487
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (26%) [HD]