STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhSPutative oxidoreductase. (534 aa)    
Predicted Functional Partners:
ydaE
Conserved protein, Rac prophage.
      
 0.875
yfcH
Putative sugar nucleotide epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
   
  
 0.809
yegV
Putative kinase; Belongs to the carbohydrate kinase PfkB family.
      
 0.804
ynjC
Putative ABC transporter permease; Probably part of the binding-protein-dependent transport system YnjCD. Probably responsible for the translocation of the substrate across the membrane.
  
     0.722
ybhP
Endo/exonuclease/phosphatase family protein; Protein involved in DNA catabolic process.
   
    0.703
yeaX
Putative YeaWX dioxygenase beta subunit, reductase component; Converts carnitine to trimethylamine and malic semialdehyde. Can also use gamma-butyrobetaine, choline and betaine as substrates.
      
 0.681
yfcG
GSH-dependent disulfide bond oxidoreductase; Exhibits a very robust glutathione (GSH)-dependent disulfide- bond reductase activity toward the model substrate, 2-hydroxyethyl disulfide; the actual physiological substrates are not known. Has also a low GSH-dependent hydroperoxidase activity toward cumene hydroperoxide, but does not reduce H(2)O(2), tert-butyl hydroperoxide, benzyl peroxide, or lauroyl peroxide. Exhibits little or no GSH transferase activity with most typical electrophilic substrates, and has no detectable transferase activity using glutathionylspermidine (GspSH) as the n [...]
   
  
 0.681
ydcK
Uncharacterized protein; Putative enzyme; Not classified; Belongs to the transferase hexapeptide repeat family.
   
    0.646
yaaW
UPF0174 family protein; Belongs to the UPF0174 family.
      
 0.644
yeeE
UPF0394 family inner membrane protein; Putative transport system permease protein.
  
   
 0.641
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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