STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flhEProton seal during flagellar secretion; Not essential for flagellar formation and function. (130 aa)    
Predicted Functional Partners:
flhB
Flagellin export apparatus, substrate specificity protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
  
  
 0.981
flhA
Putative flagellar export pore protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.975
flgJ
Flagellar rod assembly protein and murein hydrolase; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
   
  
 0.853
fliP
Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system; Belongs to the FliP/MopC/SpaP family.
   
  
 0.844
fliO
Flagellar biosynthesis; Protein involved in flagellum assembly and taxis.
   
  
 0.839
fliJ
Flagellar protein; The FliJ protein is a flagellar protein that affects chemotactic events. Mutations in FliJ results in failure to respond to chemotactic stimuli.
   
  
 0.828
fliR
Flagellar export pore protein; Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.
   
  
 0.800
flgH
Flagellar protein of basal-body outer-membrane L ring; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
   
  
 0.786
fliI
Flagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage; Belongs to the ATPase alpha/beta chains family.
   
  
 0.784
fliG
Flagellar motor switching and energizing component; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
   
  
 0.777
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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