node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
flgB | flgC | b1073 | b1074 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | 0.999 |
flgB | flgD | b1073 | b1075 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar hook assembly protein; Required for flagellar hook formation. May act as a scaffolding protein. | 0.999 |
flgB | flgE | b1073 | b1076 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar biosynthesis, hook protein; Protein involved in flagellum assembly and taxis. | 0.999 |
flgB | flgK | b1073 | b1082 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar biosynthesis, hook-filament junction protein 1; Protein involved in flagellum assembly, protein folding and taxis; Belongs to the flagella basal body rod proteins family. | 0.999 |
flgB | flgM | b1073 | b1071 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Anti-sigma factor for FliA (sigma 28); Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA; Belongs to the FlgM family. | 0.988 |
flgB | fliA | b1073 | b1922 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | RNA polymerase, sigma 28 (sigma F) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. | 0.998 |
flgB | fliC | b1073 | b1923 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar filament structural protein (flagellin); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.997 |
flgB | fliD | b1073 | b1924 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellar filament capping protein; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end; Belongs to the FliD family. | 0.999 |
flgB | fliI | b1073 | b1941 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | Flagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage; Belongs to the ATPase alpha/beta chains family. | 0.998 |
flgB | fliZ | b1073 | b1921 | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | RpoS antagonist; During the post-exponential growth phase transiently interferes with RpoS (sigma S) activity without affecting expression of RpoS itself. It is probably not an anti-sigma factor as its overexpression is detrimental in rapidly growing cells where there is almost no sigma S factor. There is a strong overlap between Crl- activated genes and FliZ-down-regulated genes. FliZ acts as a timing device for expression of the genes for the adhesive curli fimbriae by indirectly decreasing expression of the curli regulator CsgD. | 0.957 |
flgC | flgB | b1074 | b1073 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). | 0.999 |
flgC | flgD | b1074 | b1075 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar hook assembly protein; Required for flagellar hook formation. May act as a scaffolding protein. | 0.999 |
flgC | flgE | b1074 | b1076 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar biosynthesis, hook protein; Protein involved in flagellum assembly and taxis. | 0.999 |
flgC | flgK | b1074 | b1082 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar biosynthesis, hook-filament junction protein 1; Protein involved in flagellum assembly, protein folding and taxis; Belongs to the flagella basal body rod proteins family. | 0.999 |
flgC | flgM | b1074 | b1071 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Anti-sigma factor for FliA (sigma 28); Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA; Belongs to the FlgM family. | 0.964 |
flgC | fliA | b1074 | b1922 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | RNA polymerase, sigma 28 (sigma F) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. | 0.997 |
flgC | fliC | b1074 | b1923 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar filament structural protein (flagellin); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.992 |
flgC | fliD | b1074 | b1924 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellar filament capping protein; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end; Belongs to the FliD family. | 0.998 |
flgC | fliI | b1074 | b1941 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | Flagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage; Belongs to the ATPase alpha/beta chains family. | 0.998 |
flgC | fliZ | b1074 | b1921 | Flagellar biosynthesis, cell-proximal portion of basal-body rod; Protein involved in flagellum assembly and taxis. | RpoS antagonist; During the post-exponential growth phase transiently interferes with RpoS (sigma S) activity without affecting expression of RpoS itself. It is probably not an anti-sigma factor as its overexpression is detrimental in rapidly growing cells where there is almost no sigma S factor. There is a strong overlap between Crl- activated genes and FliZ-down-regulated genes. FliZ acts as a timing device for expression of the genes for the adhesive curli fimbriae by indirectly decreasing expression of the curli regulator CsgD. | 0.921 |