node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cspC | kdpC | b1823 | b0696 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | 0.429 |
cspC | minE | b1823 | b1174 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.984 |
cspC | nlpD | b1823 | b2742 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | 0.550 |
cspC | raiA | b1823 | b2597 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Cold shock protein associated with 30S ribosomal subunit; During stationary phase prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. During environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation elongation and increases translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome. Has been suggested to inhibit translation elongation by blockin [...] | 0.957 |
cspC | rmf | b1823 | b0953 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | 0.885 |
cspC | rpoN | b1823 | b3202 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC). | 0.760 |
cspC | yfcH | b1823 | b2304 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Putative sugar nucleotide epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. | 0.755 |
cspC | yobF | b1823 | b1824 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | DUF2527 family heat-induced protein. | 0.998 |
cspC | yodC | b1823 | b1957 | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | Uncharacterized protein. | 0.657 |
kdpC | cspC | b0696 | b1823 | Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | 0.429 |
kdpC | rmf | b0696 | b0953 | Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | 0.693 |
kdpC | yfcH | b0696 | b2304 | Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | Putative sugar nucleotide epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. | 0.540 |
kdpC | yodC | b0696 | b1957 | Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. | Uncharacterized protein. | 0.652 |
minE | cspC | b1174 | b1823 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. | 0.984 |
minE | nlpD | b1174 | b2742 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | 0.423 |
minE | raiA | b1174 | b2597 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Cold shock protein associated with 30S ribosomal subunit; During stationary phase prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. During environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation elongation and increases translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome. Has been suggested to inhibit translation elongation by blockin [...] | 0.879 |
minE | rmf | b1174 | b0953 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | 0.874 |
minE | rpoN | b1174 | b3202 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC). | 0.746 |
minE | yfcH | b1174 | b2304 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Putative sugar nucleotide epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. | 0.877 |
minE | yobF | b1174 | b1824 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | DUF2527 family heat-induced protein. | 0.962 |