node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dcm | vsr | b1961 | b1960 | DNA cytosine methyltransferase; This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands. | DNA mismatch endonuclease of very short patch repair; Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-C transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific; Belongs to the vsr [...] | 0.991 |
dcm | yedJ | b1961 | b1962 | DNA cytosine methyltransferase; This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands. | Putative HD superfamily phosphohydrolase. | 0.722 |
dcm | yedR | b1961 | b1963 | DNA cytosine methyltransferase; This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands. | Inner membrane protein. | 0.646 |
nudJ | yedJ | b1134 | b1962 | Bifunctional thiamine pyrimidine pyrophosphate hydrolase and thiamine pyrophosphate hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P), and hydrolysis of thiamine pyrophosphate (TPP) to thiamine monophosphate (TMP). Can hydrolyze other substrates such as MeO-HMP-PP, CF(3)-HMP-PP and MeO-TPP. Is also a non-specific nucleoside tri- and diphosphatase that releases inorganic orthophosphate; Belongs to the Nudix hydrolase family. NudJ subfamily. | Putative HD superfamily phosphohydrolase. | 0.528 |
nudJ | yedP | b1134 | b1955 | Bifunctional thiamine pyrimidine pyrophosphate hydrolase and thiamine pyrophosphate hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P), and hydrolysis of thiamine pyrophosphate (TPP) to thiamine monophosphate (TMP). Can hydrolyze other substrates such as MeO-HMP-PP, CF(3)-HMP-PP and MeO-TPP. Is also a non-specific nucleoside tri- and diphosphatase that releases inorganic orthophosphate; Belongs to the Nudix hydrolase family. NudJ subfamily. | Putative mannosyl-3-phosphoglycerate phosphatase. | 0.643 |
nudJ | ynbD | b1134 | b1411 | Bifunctional thiamine pyrimidine pyrophosphate hydrolase and thiamine pyrophosphate hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P), and hydrolysis of thiamine pyrophosphate (TPP) to thiamine monophosphate (TMP). Can hydrolyze other substrates such as MeO-HMP-PP, CF(3)-HMP-PP and MeO-TPP. Is also a non-specific nucleoside tri- and diphosphatase that releases inorganic orthophosphate; Belongs to the Nudix hydrolase family. NudJ subfamily. | Putative phosphatase inner membrane protein; Putative enzymes; Belongs to the protein-tyrosine phosphatase family. | 0.555 |
vsr | dcm | b1960 | b1961 | DNA mismatch endonuclease of very short patch repair; Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-C transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific; Belongs to the vsr [...] | DNA cytosine methyltransferase; This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands. | 0.991 |
vsr | yedJ | b1960 | b1962 | DNA mismatch endonuclease of very short patch repair; Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-C transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific; Belongs to the vsr [...] | Putative HD superfamily phosphohydrolase. | 0.698 |
vsr | yedR | b1960 | b1963 | DNA mismatch endonuclease of very short patch repair; Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-C transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific; Belongs to the vsr [...] | Inner membrane protein. | 0.580 |
yecF | yedJ | b1915 | b1962 | DUF2594 family protein. | Putative HD superfamily phosphohydrolase. | 0.620 |
yecF | yhhS | b1915 | b3473 | DUF2594 family protein. | Putative arabinose efflux transporter; Confers high-level resistance to glyphosate when overexpressed. Overexpression has no effect on intracellular arabinose concentrations. Belongs to the major facilitator superfamily. YhhS family. | 0.641 |
yedJ | dcm | b1962 | b1961 | Putative HD superfamily phosphohydrolase. | DNA cytosine methyltransferase; This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands. | 0.722 |
yedJ | nudJ | b1962 | b1134 | Putative HD superfamily phosphohydrolase. | Bifunctional thiamine pyrimidine pyrophosphate hydrolase and thiamine pyrophosphate hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P), and hydrolysis of thiamine pyrophosphate (TPP) to thiamine monophosphate (TMP). Can hydrolyze other substrates such as MeO-HMP-PP, CF(3)-HMP-PP and MeO-TPP. Is also a non-specific nucleoside tri- and diphosphatase that releases inorganic orthophosphate; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.528 |
yedJ | vsr | b1962 | b1960 | Putative HD superfamily phosphohydrolase. | DNA mismatch endonuclease of very short patch repair; Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-C transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific; Belongs to the vsr [...] | 0.698 |
yedJ | yecF | b1962 | b1915 | Putative HD superfamily phosphohydrolase. | DUF2594 family protein. | 0.620 |
yedJ | yedP | b1962 | b1955 | Putative HD superfamily phosphohydrolase. | Putative mannosyl-3-phosphoglycerate phosphatase. | 0.624 |
yedJ | yedR | b1962 | b1963 | Putative HD superfamily phosphohydrolase. | Inner membrane protein. | 0.844 |
yedJ | ygaH | b1962 | b2683 | Putative HD superfamily phosphohydrolase. | Putative L-valine exporter, norvaline resistance protein. | 0.520 |
yedJ | ygbE | b1962 | b2749 | Putative HD superfamily phosphohydrolase. | DUF3561 family inner membrane protein; Putative cytochrome oxidase subunit. | 0.509 |
yedJ | yhhS | b1962 | b3473 | Putative HD superfamily phosphohydrolase. | Putative arabinose efflux transporter; Confers high-level resistance to glyphosate when overexpressed. Overexpression has no effect on intracellular arabinose concentrations. Belongs to the major facilitator superfamily. YhhS family. | 0.530 |