STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtfAAnti-repressor for DgsA(Mlc); Involved in the regulation of ptsG expression by binding and inactivating Mlc; Belongs to the MtfA family. (265 aa)    
Predicted Functional Partners:
mlc
Glucosamine anaerobic growth regulon transcriptional repressor; Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake. Regulates the expression of malT.
   
 
 0.896
yjgH
UPF0131 family protein; Protein involved in translation.
      
 0.644
iap
Aminopeptidase in alkaline phosphatase isozyme conversion; This protein, presumably an aminopeptidase, mediates the conversion of E.coli alkaline phosphatase isozyme 1, to isozymes 2 and 3 by removing, one by one, the two N-terminal arginine residues.
  
     0.494
yojI
Microcin J25 efflux ABC transporter permease/ATPase; Mediates resistance to the antibacterial peptide microcin J25, when expressed from a multicopy vector. Functions as an efflux pump for microcin J25, with the help of the outer membrane channel TolC.
  
     0.491
yeeN
UPF0082 family protein; Belongs to the TACO1 family. YeeN subfamily.
      
 0.457
ydiF
Putative acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. May play a role in short-chain fatty acid metabolism in E.coli (By similarity). Belongs to the 3-oxoacid CoA-transferase family.
      
 0.453
ybeL
DUF1451 family protein; Putative alpha helical protein.
  
    0.447
flgA
Assembly protein for flagellar basal-body periplasmic P ring; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
  
     0.439
ycfJ
Uncharacterized protein.
  
     0.433
rspB
Starvation-sensing protein RspB; Not known; probable catabolic enzyme.
      
 0.401
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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