node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fimA | fimH | b4314 | b4320 | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | 0.997 |
fimA | flu | b4314 | b2000 | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | 0.812 |
fimA | sfmH | b4314 | b0533 | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | FimA homolog, function unknown; Part of the sfmACDHF fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes. | 0.992 |
fimA | yfaL | b4314 | b2233 | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | Adhesin; Probably an autotransporter. | 0.961 |
fimH | fimA | b4320 | b4314 | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | 0.997 |
fimH | flu | b4320 | b2000 | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | 0.813 |
fimH | sfmA | b4320 | b0530 | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | FimA homolog, function unknown; Part of the sfmACDHF fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes. | 0.995 |
fimH | yfaL | b4320 | b2233 | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | Adhesin; Probably an autotransporter. | 0.977 |
flu | fimA | b2000 | b4314 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. | 0.812 |
flu | fimH | b2000 | b4320 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Minor component of type 1 fimbriae; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | 0.813 |
flu | intE | b2000 | b1140 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | E14 prophage; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. | 0.773 |
flu | oxyR | b2000 | b3961 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Oxidative and nitrosative stress transcriptional regulator; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- [...] | 0.810 |
flu | sfmA | b2000 | b0530 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | FimA homolog, function unknown; Part of the sfmACDHF fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes. | 0.729 |
flu | sfmH | b2000 | b0533 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | FimA homolog, function unknown; Part of the sfmACDHF fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes. | 0.814 |
flu | tamB | b2000 | b4221 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Translocation and assembly module for autotransporter export, inner membrane subunit; Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane. In reconstituted TAM this subunit (Ag43, AC P39180) is not necessary for substrate penetration in the outer membrane. Substrate binding to TamA moves its POTRA domains about 30 Angstroms into the periplasm, which would deform either the outer membrane or TamB and may provide force to reset TAM. | 0.731 |
flu | yeeJ | b2000 | b1978 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Putative factor; Protein involved in regulation of transcription, DNA-dependent; Belongs to the intimin/invasin family. | 0.732 |
flu | yeeR | b2000 | b2001 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | CP4-44 prophage; putative membrane protein. | 0.979 |
flu | yfaL | b2000 | b2233 | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | Adhesin; Probably an autotransporter. | 0.895 |
intE | flu | b1140 | b2000 | E14 prophage; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. | Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin. | 0.773 |
intE | yeeJ | b1140 | b1978 | E14 prophage; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. | Putative factor; Protein involved in regulation of transcription, DNA-dependent; Belongs to the intimin/invasin family. | 0.462 |