node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmd | wcaA | b2053 | b2059 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | 0.960 |
gmd | wcaB | b2053 | b2058 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.863 |
gmd | wcaC | b2053 | b2057 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.972 |
gmd | wcaD | b2053 | b2056 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative colanic acid polymerase. | 0.897 |
gmd | wcaE | b2053 | b2055 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.960 |
gmd | wcaF | b2053 | b2054 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.972 |
gmd | wcaG | b2053 | b2052 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.999 |
gmd | wcaH | b2053 | b2051 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.999 |
gmd | wza | b2053 | b2062 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.968 |
gmd | wzc | b2053 | b2060 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.959 |
wcaA | gmd | b2059 | b2053 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.960 |
wcaA | wcaB | b2059 | b2058 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.992 |
wcaA | wcaC | b2059 | b2057 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.996 |
wcaA | wcaD | b2059 | b2056 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative colanic acid polymerase. | 0.974 |
wcaA | wcaE | b2059 | b2055 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.983 |
wcaA | wcaF | b2059 | b2054 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.975 |
wcaA | wcaG | b2059 | b2052 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.937 |
wcaA | wcaH | b2059 | b2051 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.945 |
wcaA | wza | b2059 | b2062 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.980 |
wcaA | wzc | b2059 | b2060 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.983 |