STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiBDUF418 family putative inner membrane protein; Involved in transport; To B.subtilis YxaH and YrkO. (385 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I; Protein involved in folic acid biosynthetic process; Belongs to the GTP cyclohydrolase I family.
 
  
 0.912
corA
Magnesium/nickel/cobalt transporter; Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity). Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
  
   
 0.763
wecF
TDP-Fuc4NAc:lipidIIFuc4NAc transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
   
 0.748
wecD
TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.
  
  
 0.712
ybaP
TraB family protein; Putative ligase.
  
     0.659
hyfB
Hydrogenase 4, membrane subunit; Possible component of hydrogenase 4.
      
 0.645
hyfD
Hydrogenase 4, membrane subunit; Possible component of hydrogenase 4. Belongs to the complex I subunit 5 family.
      
 0.624
galS
Galactose- and fucose-inducible galactose regulon transcriptional isorepressor; Repressor of the mgl operon. Binds galactose and D-fucose as inducers. GalS binds to an operator DNA sequence within its own coding sequence (corresponding to residues 15 to 20).
    0.623
nepI
Putative transporter; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine.
   
  
 0.580
caiT
Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines.
  
   
 0.563
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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