STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiLPutative transcriptional regulator; Transcription regulator involved in mid-term, stationary- phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as general nitrogen sources during nitrogen-limited growth. (219 aa)    
Predicted Functional Partners:
evgS
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals.
 
 
 
 0.710
rihB
Ribonucleoside hydrolase 2; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine; Belongs to the IUNH family. RihB subfamily.
  
  
 0.662
ypjA
Adhesin-like autotransporter; Putative ATP-binding component of a transport system.
  
     0.562
yifE
UPF0438 family protein; Protein involved in regulation of transcription, DNA-dependent; Belongs to the UPF0438 family.
      
 0.530
matP
Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain; Belongs to the MatP family.
      
 0.528
yfdK
Uncharacterized protein YfdK; Pseudogene, CPS-53 (KpLE1) prophage; tail fiber assembly protein fragment;Phage or Prophage Related; To E.coli YmfS.
      
 0.525
eutL
Putative ethanol utilization carboxysome structural protein; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place.
  
     0.497
arcB
Aerobic respiration control sensor protein ArcB; Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His-717 and Asp-576.
  
 
 0.493
barA
Hybrid sensory histidine kinase, in two-component regulatory system with UvrY; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay.
  
 
 0.465
yeiI
Putative kinase; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.460
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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