STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psuKPseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP). (313 aa)    
Predicted Functional Partners:
psuG
Pseudouridine 5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
 
 0.999
psuT
Putative nucleoside transporter; Could be involved in pseudouridine transport; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
  
  
 0.834
frlR
Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine.
     
 0.812
tdcR
L-threonine dehydratase operon activator protein; Probable trans-acting positive activator for the tdc operon.
      
 0.733
fruA
Fused fructose-specific PTS enzymes: IIBcomponent/IIC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
      
 0.640
yobD
UPF0266 family inner membrane protein.
      
 0.622
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta- allofuranose and beta-allopyranose; Belongs to the RbsD / FucU family. RbsD subfamily.
 
  
 0.621
frmR
Regulator protein that represses frmRAB operon; Repressor of the frmRAB operon.
      
 0.601
yjjI
DUF3029 family protein, putative glycine radical enzyme.
  
     0.581
ydiM
Putative MFS transporter, membrane protein; Putative transport system permease protein.
   
  
 0.535
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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