node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
deoC | yfbU | b4381 | b2294 | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose. Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | UPF0304 family protein. | 0.642 |
deoC | ygcR | b4381 | b2770 | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose. Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | Putative flavoprotein; May play a role in a redox process. | 0.530 |
grcA | slyD | b2579 | b3349 | Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins. | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...] | 0.461 |
grcA | yfbU | b2579 | b2294 | Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins. | UPF0304 family protein. | 0.813 |
grcA | ygcR | b2579 | b2770 | Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Putative flavoprotein; May play a role in a redox process. | 0.808 |
rbn | yfbU | b2268 | b2294 | RNase BN, tRNA processing enzyme; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities, depending on the nature of the substrate and of the added divalent cation, and on its 3'-terminal structure. Can process the 3' termini of both CCA-less and CCA-containing tRNA precursors. CCA-less tRNAs are cleaved endonucleolytically after the discriminator base, whereas residues following the CCA sequence can be removed exonucleolytically or endonucleolytically in CCA-containing molecules. Does not remove the CCA sequence. May also be involved in the degradation [...] | UPF0304 family protein. | 0.530 |
rbn | ygcR | b2268 | b2770 | RNase BN, tRNA processing enzyme; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities, depending on the nature of the substrate and of the added divalent cation, and on its 3'-terminal structure. Can process the 3' termini of both CCA-less and CCA-containing tRNA precursors. CCA-less tRNAs are cleaved endonucleolytically after the discriminator base, whereas residues following the CCA sequence can be removed exonucleolytically or endonucleolytically in CCA-containing molecules. Does not remove the CCA sequence. May also be involved in the degradation [...] | Putative flavoprotein; May play a role in a redox process. | 0.644 |
slyD | grcA | b3349 | b2579 | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...] | Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins. | 0.461 |
slyD | yfbU | b3349 | b2294 | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...] | UPF0304 family protein. | 0.705 |
slyD | ygcR | b3349 | b2770 | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...] | Putative flavoprotein; May play a role in a redox process. | 0.809 |
yajQ | yfbU | b0426 | b2294 | Phage Phi6 host factor, ATP/GTP binding protein; Binds nucleotides, may bind tRNA. | UPF0304 family protein. | 0.623 |
yajQ | ygcR | b0426 | b2770 | Phage Phi6 host factor, ATP/GTP binding protein; Binds nucleotides, may bind tRNA. | Putative flavoprotein; May play a role in a redox process. | 0.529 |
yeeX | yfbU | b2007 | b2294 | UPF0265 protein YeeX; Pseudogene, CP4-44 putative prophage remnant;Phage or Prophage Related; Belongs to the UPF0265 family. | UPF0304 family protein. | 0.696 |
yfbS | yfbT | b2292 | b2293 | Putative transport protein. | Sugar phosphatas; Sugar-phosphate phosphohydrolase that appears to contribute to butanol tolerance. Catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate. Is also able to dephosphorylate other sugar phosphates in vitro including ribose-5-phosphate (Rib5P), 2-deoxyribose-5-phosphate, fructose-1-phosphate (Fru1P), fructose-6-phosphate (Fru6P), and glucose-6-phosphate (Glu6P). Selectively hydrolyzes beta-D-glucose-1-phosphate (bGlu1P) and has no activity with the alpha form. | 0.810 |
yfbS | yfbU | b2292 | b2294 | Putative transport protein. | UPF0304 family protein. | 0.863 |
yfbS | yfbV | b2292 | b2295 | Putative transport protein. | UPF0208 family inner membrane protein. | 0.416 |
yfbT | yfbS | b2293 | b2292 | Sugar phosphatas; Sugar-phosphate phosphohydrolase that appears to contribute to butanol tolerance. Catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate. Is also able to dephosphorylate other sugar phosphates in vitro including ribose-5-phosphate (Rib5P), 2-deoxyribose-5-phosphate, fructose-1-phosphate (Fru1P), fructose-6-phosphate (Fru6P), and glucose-6-phosphate (Glu6P). Selectively hydrolyzes beta-D-glucose-1-phosphate (bGlu1P) and has no activity with the alpha form. | Putative transport protein. | 0.810 |
yfbT | yfbU | b2293 | b2294 | Sugar phosphatas; Sugar-phosphate phosphohydrolase that appears to contribute to butanol tolerance. Catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate. Is also able to dephosphorylate other sugar phosphates in vitro including ribose-5-phosphate (Rib5P), 2-deoxyribose-5-phosphate, fructose-1-phosphate (Fru1P), fructose-6-phosphate (Fru6P), and glucose-6-phosphate (Glu6P). Selectively hydrolyzes beta-D-glucose-1-phosphate (bGlu1P) and has no activity with the alpha form. | UPF0304 family protein. | 0.937 |
yfbT | yfbV | b2293 | b2295 | Sugar phosphatas; Sugar-phosphate phosphohydrolase that appears to contribute to butanol tolerance. Catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate. Is also able to dephosphorylate other sugar phosphates in vitro including ribose-5-phosphate (Rib5P), 2-deoxyribose-5-phosphate, fructose-1-phosphate (Fru1P), fructose-6-phosphate (Fru6P), and glucose-6-phosphate (Glu6P). Selectively hydrolyzes beta-D-glucose-1-phosphate (bGlu1P) and has no activity with the alpha form. | UPF0208 family inner membrane protein. | 0.558 |
yfbU | deoC | b2294 | b4381 | UPF0304 family protein. | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose. Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 0.642 |