node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cvpA | dedD | b2313 | b2314 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Membrane-anchored periplasmic protein involved in septation; Non-essential cell division protein that could be required for efficient cell constriction; Belongs to the DedD family. | 0.760 |
cvpA | purC | b2313 | b2476 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | 0.887 |
cvpA | purE | b2313 | b0523 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the AIR carboxylase family. Class I subfamily. | 0.838 |
cvpA | purF | b2313 | b2312 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. Can also use NH(3) in place of glutamine. | 0.998 |
cvpA | purH | b2313 | b4006 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase; Protein involved in purine nucleotide biosynthetic process and nucleobase, nucleoside and nucleotide interconversion. | 0.774 |
cvpA | purK | b2313 | b0522 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.773 |
cvpA | purL | b2313 | b2557 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.955 |
cvpA | purM | b2313 | b2499 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Phosphoribosylaminoimidazole synthetase = AIR synthetase; Protein involved in purine nucleotide biosynthetic process; Belongs to the AIR synthase family. | 0.954 |
cvpA | purN | b2313 | b2500 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family. | 0.817 |
cvpA | purT | b2313 | b1849 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. PurT is also able to cleave acetyl phosphate and carbamoyl phosphate to produce ATP with acetate and carbamate, respectively; Belongs to the PurK/PurT family. | 0.839 |
dedD | cvpA | b2314 | b2313 | Membrane-anchored periplasmic protein involved in septation; Non-essential cell division protein that could be required for efficient cell constriction; Belongs to the DedD family. | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | 0.760 |
dedD | purF | b2314 | b2312 | Membrane-anchored periplasmic protein involved in septation; Non-essential cell division protein that could be required for efficient cell constriction; Belongs to the DedD family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. Can also use NH(3) in place of glutamine. | 0.646 |
purC | cvpA | b2476 | b2313 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | 0.887 |
purC | purE | b2476 | b0523 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the AIR carboxylase family. Class I subfamily. | 0.999 |
purC | purF | b2476 | b2312 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. Can also use NH(3) in place of glutamine. | 0.991 |
purC | purH | b2476 | b4006 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase; Protein involved in purine nucleotide biosynthetic process and nucleobase, nucleoside and nucleotide interconversion. | 0.997 |
purC | purK | b2476 | b0522 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.998 |
purC | purL | b2476 | b2557 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.998 |
purC | purM | b2476 | b2499 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | Phosphoribosylaminoimidazole synthetase = AIR synthetase; Protein involved in purine nucleotide biosynthetic process; Belongs to the AIR synthase family. | 0.998 |
purC | purN | b2476 | b2500 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase; Protein involved in purine nucleotide biosynthetic process. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family. | 0.993 |