node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaC | avtA | b2379 | b3572 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.808 |
alaC | lysA | b2379 | b2838 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | 0.473 |
alaC | maeB | b2379 | b2463 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Malic enzyme: putative oxidoreductase/phosphotransacetylase; Putative multimodular enzyme; In the N-terminal section; belongs to the malic enzymes family. | 0.468 |
alaC | metB | b2379 | b3939 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Cystathionine gamma-synthase, PLP-dependent; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia. | 0.565 |
alaC | metL | b2379 | b3940 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Bifunctional aspartokinase/homoserine dehydrogenase 2; Aspartokinase II and homoserine dehydrogenase II; Protein involved in methionine biosynthetic process and homoserine biosynthetic process. | 0.469 |
alaC | metN | b2379 | b0199 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. It has also been shown to be involved in formyl-L-methionine transport. Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | 0.552 |
alaC | sgrR | b2379 | b0069 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Transcriptional DNA-binding transcriptional activator of sgrS sRNA; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions; this repression likely provides one measure of control over sgrR at the level of synthesis. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute- binding domain. | 0.570 |
alaC | trpC | b2379 | b1262 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain. | 0.592 |
alaC | tyrA | b2379 | b2600 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Chorismate mutase-T and prephenate dehydrogenase; Protein involved in L-phenylalanine biosynthetic process and tyrosine biosynthetic process. | 0.502 |
alaC | ypdE | b2379 | b2384 | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | Aminopeptidase; Has a broad aminopeptidase activity on non-blocked peptides by progressively cleaving amino acids off the peptide substrate. Aminopeptidase activity stops at the residue before the first proline in the peptide. Cannot cleave when proline is the first N-terminal residue. | 0.640 |
avtA | alaC | b3572 | b2379 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.808 |
avtA | tyrA | b3572 | b2600 | Valine-pyruvate aminotransferase; Involved in the biosynthesis of alanine. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Chorismate mutase-T and prephenate dehydrogenase; Protein involved in L-phenylalanine biosynthetic process and tyrosine biosynthetic process. | 0.414 |
lysA | alaC | b2838 | b2379 | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.473 |
lysA | metB | b2838 | b3939 | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | Cystathionine gamma-synthase, PLP-dependent; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia. | 0.445 |
lysA | metL | b2838 | b3940 | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | Bifunctional aspartokinase/homoserine dehydrogenase 2; Aspartokinase II and homoserine dehydrogenase II; Protein involved in methionine biosynthetic process and homoserine biosynthetic process. | 0.882 |
lysA | trpC | b2838 | b1262 | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | Indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain. | 0.628 |
lysA | tyrA | b2838 | b2600 | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate; Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily. | Chorismate mutase-T and prephenate dehydrogenase; Protein involved in L-phenylalanine biosynthetic process and tyrosine biosynthetic process. | 0.444 |
maeB | alaC | b2463 | b2379 | Malic enzyme: putative oxidoreductase/phosphotransacetylase; Putative multimodular enzyme; In the N-terminal section; belongs to the malic enzymes family. | Glutamate-pyruvate aminotransferase; Involved in the biosynthesis of alanine. | 0.468 |
maeB | metL | b2463 | b3940 | Malic enzyme: putative oxidoreductase/phosphotransacetylase; Putative multimodular enzyme; In the N-terminal section; belongs to the malic enzymes family. | Bifunctional aspartokinase/homoserine dehydrogenase 2; Aspartokinase II and homoserine dehydrogenase II; Protein involved in methionine biosynthetic process and homoserine biosynthetic process. | 0.435 |
maeB | tyrA | b2463 | b2600 | Malic enzyme: putative oxidoreductase/phosphotransacetylase; Putative multimodular enzyme; In the N-terminal section; belongs to the malic enzymes family. | Chorismate mutase-T and prephenate dehydrogenase; Protein involved in L-phenylalanine biosynthetic process and tyrosine biosynthetic process. | 0.533 |