node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cvpA | cysZ | b2313 | b2413 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.449 |
cvpA | holC | b2313 | b4259 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.683 |
cvpA | zipA | b2313 | b2412 | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | FtsZ stabilizer; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL and FtsN. ZipA overproduction protects FtsZ from degradation by ClpP by preventing recognition by ClpX. Does not affect the GTPase activity of FtsZ. | 0.463 |
cysK | cysZ | b2414 | b2413 | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; (Microbial infection) In addition to its role in cysteine synthesis, stimulates the tRNase activity of CdiA-CT from E.coli strain 536 / UPEC; stimulation does not require O-acetylserine sulfhydrylase activity. CdiA is the toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion (experiments done in strains BW25113 [...] | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.484 |
cysZ | cvpA | b2413 | b2313 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | 0.449 |
cysZ | cysK | b2413 | b2414 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; (Microbial infection) In addition to its role in cysteine synthesis, stimulates the tRNase activity of CdiA-CT from E.coli strain 536 / UPEC; stimulation does not require O-acetylserine sulfhydrylase activity. CdiA is the toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion (experiments done in strains BW25113 [...] | 0.484 |
cysZ | holC | b2413 | b4259 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.507 |
cysZ | ibaG | b2413 | b3190 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | Acid stress protein; Involved in cell resistance against acid stress. | 0.504 |
cysZ | ligA | b2413 | b2411 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | DNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.404 |
cysZ | ygiM | b2413 | b3055 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | SH3 domain protein. | 0.571 |
cysZ | zipA | b2413 | b2412 | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | FtsZ stabilizer; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL and FtsN. ZipA overproduction protects FtsZ from degradation by ClpP by preventing recognition by ClpX. Does not affect the GTPase activity of FtsZ. | 0.610 |
holC | cvpA | b4259 | b2313 | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Colicin V production protein; Required for colicin V production from plasmid IncFI ColV3- K30. | 0.683 |
holC | cysZ | b4259 | b2413 | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.507 |
holC | ygiM | b4259 | b3055 | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | SH3 domain protein. | 0.423 |
holC | zipA | b4259 | b2412 | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | FtsZ stabilizer; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL and FtsN. ZipA overproduction protects FtsZ from degradation by ClpP by preventing recognition by ClpX. Does not affect the GTPase activity of FtsZ. | 0.560 |
ibaG | cysZ | b3190 | b2413 | Acid stress protein; Involved in cell resistance against acid stress. | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.504 |
ligA | cysZ | b2411 | b2413 | DNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.404 |
ligA | zipA | b2411 | b2412 | DNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | FtsZ stabilizer; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL and FtsN. ZipA overproduction protects FtsZ from degradation by ClpP by preventing recognition by ClpX. Does not affect the GTPase activity of FtsZ. | 0.599 |
ygiM | cysZ | b3055 | b2413 | SH3 domain protein. | Sulfate transporter, sulfite inhibited; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. Does not transport thiosulfate. Belongs to the CysZ family. | 0.571 |
ygiM | holC | b3055 | b4259 | SH3 domain protein. | DNA polymerase III, chi subunit; Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.423 |