STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfgGUncharacterized protein. (63 aa)    
Predicted Functional Partners:
yfgF
cyclic-di-GMP phosphodiesterase, anaerobic; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG. Truncated proteins consisting of the GGDEF/EAL domains (residues 319-747) or of the EAL domain alone (481-747) have c-di-GMP phosphodiesterase activity. They do not have diguanylate cyclase activity. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.
  
  
 0.764
ydjX
TVP38/TMEM64 family inner membrane protein; Belongs to the TVP38/TMEM64 family.
   
  
 0.507
ygeH
Putative transcriptional regulator; Putative invasion protein.
      
 0.505
yraH
Putative fimbrial-like adhesin protein; Part of the yraHIJK fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim operon.
      
 0.505
insL1
IS186 transposase; Involved in the transposition of the insertion sequence IS186.
      
 0.503
ydhY
Putative 4Fe-4S ferridoxin-type protein; Putative oxidoreductase, Fe-S subunit.
      
 0.501
agaI
Putative galactosamine-6-phosphate isomerase; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
      
 0.473
ydfZ
Selenoprotein, function unknown.
      
 0.457
yjhB
Putative MFS transporter, membrane protein; Putative transport protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.457
yjcZ
YjcZ family protein; yhjH motility defect suppressor.
      
 0.454
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.