STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yphGDUF4380 domain-containing TPR repeat protein. (1093 aa)    
Predicted Functional Partners:
yphH
Putative NAGC-like transcriptional regulator; Protein involved in regulation of transcription, DNA-dependent; Belongs to the ROK (NagC/XylR) family.
 
  
 0.933
yeiW
UPF0153 cysteine cluster protein.
    
 
 0.895
yjiS
DUF1127 family protein.
      
 0.811
yjhG
Putative dehydratase; Catalyzes the dehydration of D-xylonic acid to form 2- dehydro-3-deoxy-D-pentonate.
 
   
 0.676
yphF
Putative sugar ABC transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YphDEF; Belongs to the bacterial solute-binding protein 2 family.
 
    0.657
ycfT
Inner membrane protein.
  
    0.601
yphB
Mutarotase superfamily protein, YphB family.
 
    0.589
yphC
Putative oxidoreductase.
 
    0.557
yghA
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.530
glgS
Motility and biofilm regulator; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
      
 0.522
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.