node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdh | cdsA | b3918 | b0175 | CDP-diacylglycerol phosphotidylhydrolase. | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | 0.924 |
cdh | pgsA | b3918 | b1912 | CDP-diacylglycerol phosphotidylhydrolase. | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
cdh | pssA | b3918 | b2585 | CDP-diacylglycerol phosphotidylhydrolase. | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | 0.912 |
cdsA | cdh | b0175 | b3918 | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | CDP-diacylglycerol phosphotidylhydrolase. | 0.924 |
cdsA | pgsA | b0175 | b1912 | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.993 |
cdsA | plsB | b0175 | b4041 | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | Glycerol-3-phosphate O-acyltransferase; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. Belongs to the GPAT/DAPAT family. | 0.751 |
cdsA | psd | b0175 | b4160 | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Only decarboxylates the lipid-linked form of the serine moiety, and not serine alone or derivatives like phosphoserine or glycerophosphoserine. | 0.918 |
cdsA | pssA | b0175 | b2585 | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | 0.984 |
glyA | pssA | b2551 | b2585 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of allothreonine and 3-phenylserine. Also catalyzes the irreversible conversion of 5,10-m [...] | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | 0.926 |
glyA | sdaB | b2551 | b2797 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of allothreonine and 3-phenylserine. Also catalyzes the irreversible conversion of 5,10-m [...] | L-serine dehydratase 2; Deaminates also threonine, particularly when it is present in high concentration; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.962 |
glyA | serB | b2551 | b4388 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of allothreonine and 3-phenylserine. Also catalyzes the irreversible conversion of 5,10-m [...] | 3-phosphoserine phosphatase; Catalyzes the dephosphorylation of phosphoserine (P-Ser). Also catalyzes the hydrolysis of phosphothreonine (P-Thr). Belongs to the HAD-like hydrolase superfamily. SerB family. | 0.984 |
glyA | tdcG | b2551 | b4471 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of allothreonine and 3-phenylserine. Also catalyzes the irreversible conversion of 5,10-m [...] | L-serine dehydratase; Protein involved in cellular amino acid catabolic process. | 0.963 |
glyA | trpA | b2551 | b1260 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of allothreonine and 3-phenylserine. Also catalyzes the irreversible conversion of 5,10-m [...] | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family. | 0.947 |
pgsA | cdh | b1912 | b3918 | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diacylglycerol phosphotidylhydrolase. | 0.900 |
pgsA | cdsA | b1912 | b0175 | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | 0.993 |
pgsA | plsB | b1912 | b4041 | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Glycerol-3-phosphate O-acyltransferase; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. Belongs to the GPAT/DAPAT family. | 0.658 |
pgsA | psd | b1912 | b4160 | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Only decarboxylates the lipid-linked form of the serine moiety, and not serine alone or derivatives like phosphoserine or glycerophosphoserine. | 0.936 |
pgsA | pssA | b1912 | b2585 | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process. | 0.989 |
plsB | cdsA | b4041 | b0175 | Glycerol-3-phosphate O-acyltransferase; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. Belongs to the GPAT/DAPAT family. | CDP-diglyceride synthetase; Protein involved in phospholipid biosynthetic process. | 0.751 |
plsB | pgsA | b4041 | b1912 | Glycerol-3-phosphate O-acyltransferase; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. Belongs to the GPAT/DAPAT family. | Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.658 |