STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfjICP4-57 prophage; uncharacterized protein. (469 aa)    
Predicted Functional Partners:
yfjJ
CP4-57 prophage; uncharacterized protein; To E.coli YagK.
  
  
 0.967
yafZ
UPF0380 protein YafZ; CP4-6 prophage; putative DNA-binding transcriptional regulator;Phage or Prophage Related; Belongs to the UPF0380 family.
 
  
 0.908
alpA
CP4-57 prophage; Positive regulator of the expression of the slpA gene. When overexpressed, leads to suppression of the capsule overproduction and UV sensitivity phenotypes of cells mutant for the Lon ATP-dependent protease. Part of the cryptic P4-like prophage CP4-57. Overexpression of AlpA leads to excision of the CP4-57 prophage by IntA. This inactivates ssrA (the gene upstream of the prophage) that encodes tmRNA which is required to rescue stalled ribosomes in a process known as trans- translation.
  
  
 0.689
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
   0.633
ynbB
Putative CDP-diglyceride synthase; Putative phosphatidate cytidiltransferase; Protein involved in nucleobase, nucleoside and nucleotide interconversion.
   
  
 0.631
ykfF
CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family.
      
 0.621
bglH
Carbohydrate-specific outer membrane porin, cryptic; Part of a cryptic operon that is poorly expressed in vivo. May be an ancestral sugar porin with a broad carbohydrate specificity; it binds aromatic beta-D-glucosides such as arbutin and salicin, but with low affinity compared to the binding of maltooligosaccharides to the LamB porin.
 
     0.561
stfP
E14 prophage; uncharacterized protein; To E.coli YfdL and M.jannaschii MJ0347.
   
  
 0.532
ybbP
Putative ABC transporter permease; Putative oxidoreductase.
      
 0.530
ydbD
PF10971 family putative periplasmic methylglyoxal resistance protein; To E.coli YkiA.
      
 0.529
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.