STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqaBfructose-1-P and 6-phosphogluconate phosphatase; Catalyzes strongly the dephosphorylation of fructose-1- phosphate (Fru1P) and slightly the dephosphorylation of 6- phosphogluconate (6P-Glu). It has low beta-phosphoglucomutase activity. (188 aa)    
Predicted Functional Partners:
yqaA
COG1238 family inner membrane protein.
 
    0.981
gshA
Glutamate-cysteine ligase; Protein involved in glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
    
 0.939
ycjT
Putative family 65 glycosyl hydrolase; In vitro catalyzes the phosphorolysis of D-kojibiose into beta-D-glucose 1-phosphate and D-glucose. No other disaccharides tested substitute for D-kojibiose. In the reverse direction disaccharides can be formed from beta-D-glucose 1-phosphate plus D-glucose, L-sorbose, D- sorbitol, L-iditol or 1,5-anhydro-D-glucitol, but with low efficiency. The beta-D-glucose 1-phosphate product is the substrate for YcjU (AC P77366), the next apparent enzyme in the putative biochemical pathway encoded in this locus (yjcM to ycjW).
  
 0.759
yieH
Phosphoenolpyruvate and 6-phosphogluconate phosphatase; Catalyzes strongly the dephosphorylation of 6- phosphogluconate (6P-Glu) and slightly the dephosphorylation of dihydroxyacetone phosphate (DHAP) and phosphoenolpyruvate (PEP). Also hydrolyzes both purines (GMP and IMP) and pyrimidines as secondary substrates.
  
     0.757
ydcF
DUF218 superfamily protein, SAM-binding; Binds S-adenosyl-L-methionine (AdoMet); To S.coelicolor SCO4629.
  
  
 0.578
slyX
Host factor for lysis of phiX174 infection; Belongs to the SlyX family.
      
 0.541
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Also catalyzes the dephosphorylation of phospho- serine in vitro ; Belongs to the aldolase class II family. RhaD subfamily.
  
  
 0.526
trxA
Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
    
   0.499
ybgJ
Putative allophanate hydrolase, subunit 1; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the PxpB family.
      
 0.451
yeeN
UPF0082 family protein; Belongs to the TACO1 family. YeeN subfamily.
  
   
 0.441
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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