node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glpK | ygcP | b3926 | b2768 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP; Belongs to the FGGY kinase family. | Putative anti-terminator regulatory protein. | 0.497 |
lolB | ygcP | b1209 | b2768 | Lipoprotein localization factor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability; Belongs to the LolB family. | Putative anti-terminator regulatory protein. | 0.505 |
pncA | ygcP | b1768 | b2768 | Nicotinamidase/pyrazinamidase; Catalyzes the deamidation of nicotinamide (NAM) into nicotinate. Likely functions in the cyclical salvage pathway for production of NAD from nicotinamide. | Putative anti-terminator regulatory protein. | 0.538 |
ptrA | ygcP | b2821 | b2768 | Protease III; Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. | Putative anti-terminator regulatory protein. | 0.623 |
queD | ygcN | b2765 | b2766 | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS); Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP. | Putative oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone; Belongs to the ETF-QO/FixC family. | 0.566 |
queD | ygcO | b2765 | b2767 | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS); Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP. | Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR. | 0.558 |
queD | ygcP | b2765 | b2768 | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS); Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP. | Putative anti-terminator regulatory protein. | 0.527 |
ygcE | ygcP | b2776 | b2768 | Putative kinase; Belongs to the FGGY kinase family. | Putative anti-terminator regulatory protein. | 0.681 |
ygcE | ygcU | b2776 | b4463 | Putative kinase; Belongs to the FGGY kinase family. | Putative FAD-linked oxidoreductase; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.831 |
ygcE | yqcE | b2776 | b2775 | Putative kinase; Belongs to the FGGY kinase family. | Putative MFS transporter, inner membrane protein; Putative transport protein. | 0.856 |
ygcN | queD | b2766 | b2765 | Putative oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone; Belongs to the ETF-QO/FixC family. | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS); Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP. | 0.566 |
ygcN | ygcO | b2766 | b2767 | Putative oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone; Belongs to the ETF-QO/FixC family. | Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR. | 0.984 |
ygcN | ygcP | b2766 | b2768 | Putative oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone; Belongs to the ETF-QO/FixC family. | Putative anti-terminator regulatory protein. | 0.740 |
ygcO | queD | b2767 | b2765 | Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR. | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS); Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP. | 0.558 |
ygcO | ygcN | b2767 | b2766 | Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR. | Putative oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone; Belongs to the ETF-QO/FixC family. | 0.984 |
ygcO | ygcP | b2767 | b2768 | Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR. | Putative anti-terminator regulatory protein. | 0.805 |
ygcP | glpK | b2768 | b3926 | Putative anti-terminator regulatory protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP; Belongs to the FGGY kinase family. | 0.497 |
ygcP | lolB | b2768 | b1209 | Putative anti-terminator regulatory protein. | Lipoprotein localization factor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability; Belongs to the LolB family. | 0.505 |
ygcP | pncA | b2768 | b1768 | Putative anti-terminator regulatory protein. | Nicotinamidase/pyrazinamidase; Catalyzes the deamidation of nicotinamide (NAM) into nicotinate. Likely functions in the cyclical salvage pathway for production of NAD from nicotinamide. | 0.538 |
ygcP | ptrA | b2768 | b2821 | Putative anti-terminator regulatory protein. | Protease III; Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. | 0.623 |