STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygcSPutative MFS sugar transporter; Putative transport protein. (445 aa)    
Predicted Functional Partners:
ygcR
Putative flavoprotein; May play a role in a redox process.
  
  
 0.908
ygcQ
Putative flavoprotein; May play a role in a redox process; Belongs to the ETF alpha-subunit/FixB family.
  
    0.779
ygcU
Putative FAD-linked oxidoreductase; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
     0.735
kgtP
Alpha-ketoglutarate transporter; Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system). Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
  
   
 0.651
ydeE
Putative transporter; A transporter able to export peptides. When overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide. Belongs to the major facilitator superfamily.
      
 0.622
ycaD
Putative MFS transporter, inner membrane protein.
      
 0.593
shiA
Shikimate transporter; Pseudogene, glycosyltransferase homology.
  
   
 0.537
mhpT
3-hydroxyphenylpropionic transporter; Uptake of 3-(3-hydroxyphenyl)propionate (3HPP) across the cytoplasmic membrane. Transport is driven by the proton motive force. Does not transport benzoate, 3-hydroxybenzoate or gentisate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
  
  
0.528
yjjQ
Putative regulator.
   
  
 0.510
ygcW
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    0.508
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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