node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hyaA | hyaC | b0972 | b0974 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | 0.999 |
hyaA | hyaD | b0972 | b0975 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 1 maturation protease; Protease involved in the C-terminal processing of HyaB, the large subunit of hydrogenase 1; Belongs to the peptidase A31 family. | 0.999 |
hyaA | hybA | b0972 | b2996 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 2 4Fe-4S ferredoxin-type component; Participates in the periplasmic electron-transferring activity of hydrogenase 2 during its catalytic turnover. | 0.908 |
hyaA | hybB | b0972 | b2995 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Putative hydrogenase 2 cytochrome b type component; Probable b-type cytochrome; Belongs to the NrfD family. | 0.870 |
hyaA | hybC | b0972 | b2994 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 2, large subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD2 is involved in hydrogen uptake; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.999 |
hyaA | hybD | b0972 | b2993 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Maturation protease for hydrogenase 2; Protease involved in the C-terminal processing of HybC, the large subunit of hydrogenase 2. Specifically cleaves off a 15 amino acid peptide from the C-terminus of the precursor of HybC; Belongs to the peptidase A31 family. | 0.836 |
hyaA | hybE | b0972 | b2992 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 2-specific chaperone; Member of hyb operon. | 0.655 |
hyaA | hybF | b0972 | b2991 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. HybF is involved in maturation of hydrogenases 1 and 2. It may partially substitute for the function of HypA and vice versa. | 0.681 |
hyaA | hybO | b0972 | b2997 | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | Hydrogenase 2, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD2 is involved in hydrogen uptake; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | 0.927 |
hyaC | hyaA | b0974 | b0972 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | 0.999 |
hyaC | hyaD | b0974 | b0975 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 1 maturation protease; Protease involved in the C-terminal processing of HyaB, the large subunit of hydrogenase 1; Belongs to the peptidase A31 family. | 0.999 |
hyaC | hybA | b0974 | b2996 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 2 4Fe-4S ferredoxin-type component; Participates in the periplasmic electron-transferring activity of hydrogenase 2 during its catalytic turnover. | 0.721 |
hyaC | hybB | b0974 | b2995 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Putative hydrogenase 2 cytochrome b type component; Probable b-type cytochrome; Belongs to the NrfD family. | 0.780 |
hyaC | hybC | b0974 | b2994 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 2, large subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD2 is involved in hydrogen uptake; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.976 |
hyaC | hybD | b0974 | b2993 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Maturation protease for hydrogenase 2; Protease involved in the C-terminal processing of HybC, the large subunit of hydrogenase 2. Specifically cleaves off a 15 amino acid peptide from the C-terminus of the precursor of HybC; Belongs to the peptidase A31 family. | 0.873 |
hyaC | hybE | b0974 | b2992 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 2-specific chaperone; Member of hyb operon. | 0.644 |
hyaC | hybF | b0974 | b2991 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. HybF is involved in maturation of hydrogenases 1 and 2. It may partially substitute for the function of HypA and vice versa. | 0.618 |
hyaC | hybO | b0974 | b2997 | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | Hydrogenase 2, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD2 is involved in hydrogen uptake; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | 0.975 |
hyaD | hyaA | b0975 | b0972 | Hydrogenase 1 maturation protease; Protease involved in the C-terminal processing of HyaB, the large subunit of hydrogenase 1; Belongs to the peptidase A31 family. | Hydrogenase 1, small subunit; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | 0.999 |
hyaD | hyaC | b0975 | b0974 | Hydrogenase 1 maturation protease; Protease involved in the C-terminal processing of HyaB, the large subunit of hydrogenase 1; Belongs to the peptidase A31 family. | Hydrogenase 1, b-type cytochrome subunit; Probable b-type cytochrome; Belongs to the HupC/HyaC/HydC family. | 0.999 |