node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
allS | cynR | b0504 | b0338 | allD operon transcriptional activator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter; Belongs to the LysR transcriptional regulatory family. | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | 0.452 |
allS | xapR | b0504 | b2405 | allD operon transcriptional activator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter; Belongs to the LysR transcriptional regulatory family. | Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. | 0.414 |
allS | yqjI | b0504 | b3071 | allD operon transcriptional activator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter; Belongs to the LysR transcriptional regulatory family. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.459 |
betI | cynR | b0313 | b0338 | Choline-inducible betIBA-betT divergent operon transcriptional repressor; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | 0.594 |
betI | yqjI | b0313 | b3071 | Choline-inducible betIBA-betT divergent operon transcriptional repressor; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.404 |
cynR | allS | b0338 | b0504 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | allD operon transcriptional activator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter; Belongs to the LysR transcriptional regulatory family. | 0.452 |
cynR | betI | b0338 | b0313 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | Choline-inducible betIBA-betT divergent operon transcriptional repressor; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. | 0.594 |
cynR | xapR | b0338 | b2405 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. | 0.409 |
cynR | yqjI | b0338 | b3071 | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.526 |
feaR | yqjI | b1384 | b3071 | Transcriptional activator for tynA and feaB; Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.530 |
murR | yqjI | b2427 | b3071 | Repressor for murPQ, MurNAc 6-P inducible; Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6- phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator. Also represses its own transcription. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.418 |
nadR | yqjI | b4390 | b3071 | Trifunctional NAD biosynthesis/regulator protein NadR; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity [...] | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.457 |
rbbA | yqjI | b3486 | b3071 | Ribosome-associated ATPase: ATP-binding protein/ATP-binding membrane protein; Exhibits an intrinsic ATPase activity that is stimulated by both 70S ribosomes and 30S ribosomal subunits. Could be involved in protein-chain elongation and in release of deacyl-tRNA from ribosomes after peptide bond synthesis. Stimulates the synthesis of polyphenylalanine in vitro; In the C-terminal section; belongs to the ABC-2 integral membrane protein family. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.417 |
xapR | allS | b2405 | b0504 | Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. | allD operon transcriptional activator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter; Belongs to the LysR transcriptional regulatory family. | 0.414 |
xapR | cynR | b2405 | b0338 | Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. | Transcriptional activator of cyn operon; Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region. | 0.409 |
xapR | yqjI | b2405 | b3071 | Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.511 |
yqfB | yqjH | b2900 | b3070 | UPF0267 family protein; Belongs to the UPF0267 family. | Putative siderophore interacting protein; Plays a role in iron homeostasis under excess nickel conditions; Belongs to the SIP oxidoreductase family. | 0.618 |
yqfB | yqjI | b2900 | b3071 | UPF0267 family protein; Belongs to the UPF0267 family. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.518 |
yqjH | yqfB | b3070 | b2900 | Putative siderophore interacting protein; Plays a role in iron homeostasis under excess nickel conditions; Belongs to the SIP oxidoreductase family. | UPF0267 family protein; Belongs to the UPF0267 family. | 0.618 |
yqjH | yqjI | b3070 | b3071 | Putative siderophore interacting protein; Plays a role in iron homeostasis under excess nickel conditions; Belongs to the SIP oxidoreductase family. | PadR family putative transcriptional regulator; Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression. | 0.984 |