node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
accC | dusB | b3256 | b3260 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.852 |
accC | fis | b3256 | b3261 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | 0.797 |
accC | panF | b3256 | b3258 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.761 |
accC | prmA | b3256 | b3259 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Methyltransferase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11. | 0.781 |
accC | yhdT | b3256 | b3257 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | DUF997 family putative inner membrane protein; To H.influenzae HI_0974B. | 0.773 |
dusB | accC | b3260 | b3256 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.852 |
dusB | fis | b3260 | b3261 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | 0.999 |
dusB | panF | b3260 | b3258 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.815 |
dusB | prmA | b3260 | b3259 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Methyltransferase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11. | 0.864 |
dusB | yhdT | b3260 | b3257 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | DUF997 family putative inner membrane protein; To H.influenzae HI_0974B. | 0.819 |
fis | accC | b3261 | b3256 | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.797 |
fis | dusB | b3261 | b3260 | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.999 |
fis | panF | b3261 | b3258 | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.847 |
fis | prmA | b3261 | b3259 | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | Methyltransferase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11. | 0.883 |
fis | yhdT | b3261 | b3257 | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | DUF997 family putative inner membrane protein; To H.influenzae HI_0974B. | 0.846 |
panF | accC | b3258 | b3256 | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.761 |
panF | dusB | b3258 | b3260 | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.815 |
panF | fis | b3258 | b3261 | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin- mediated DNA inversion. Prevents initiation of DNA replication from oriC. Binds to hundreds of transcriptionally active and inactive AT- rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Belongs to the transcriptional regulatory Fis family. | 0.847 |
panF | prmA | b3258 | b3259 | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Methyltransferase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11. | 0.966 |
panF | ydhT | b3258 | b1669 | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | FNR, Nar, NarP-regulated protein; putative subunit of YdhYVWXUT oxidoreductase complex. | 0.644 |